N-Boc-ethanolamine
N-Boc-ethanolamine (CAS: 26690-80-2) is a protected amino alcohol with the linear formula (CH₃)₃COCONHCH₂CH₂OH and a molecular weight of 161.20 g/mol. This difunctional reagent is valuable in organic synthesis, particularly for preparing phosphatidyl ethanolamines and ornithine. It is supplied by Tech Serve Solutions with an assay of ≥96.0% (GC).
- IUPAC
- N-(tert-Butoxycarbonyl)ethanolamine,tert-Butyl N-(2-hydroxyethyl)carbamate,Boc-2-aminoethanol,Boc-glycinol
- Synonyms
- tert-Butyl N-(2-hydroxyethyl)carbamateBoc-2-aminoethanolBoc-glycinolN-(tert-Butoxycarbonyl)ethanolamine
Synthesis of Phosphatidyl Ethanolamines
N-Boc-ethanolamine serves as a key intermediate in the synthesis of phosphatidyl ethanolamines, important components of cell membranes. Its protected amine allows for selective reactions at the hydroxyl group.
Preparation of Ornithine Derivatives
This compound is employed in the synthetic routes to ornithine, a non-proteinogenic amino acid. The Boc protecting group facilitates controlled functionalisation.
Bifunctional Linker Applications
As a bifunctional molecule containing both a protected amine and a hydroxyl group, N-Boc-ethanolamine can act as a linker in complex molecular constructions.
Organic Building Block
It functions as a versatile building block in general organic synthesis, enabling the introduction of an ethanolamine moiety with amine protection.
| Molecular weight | 161.20 |
|---|---|
| Linear formula | (CH3)3COCONHCH2CH2OH |
| Assay | ≥96.0% (GC) |
| Density | 1.042 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.449(lit.)n20/D 1.450 |
| Application | Amine protected, difunctional reagent employed in the synthesis of phosphatidyl ethanolamines and ornithine.1,2 |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 109 °C / 228.2 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-37/38-41 |
| Safety statements (S) | 26-39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-ethanolamine used for?
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N-Boc-ethanolamine is used as a protected amine and alcohol reagent in organic synthesis, notably for preparing phosphatidyl ethanolamines and ornithine derivatives.
What are the CAS number and chemical formula for N-Boc-ethanolamine?
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The CAS number is 26690-80-2 and the linear formula is (CH₃)₃COCONHCH₂CH₂OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-ethanolamine with a purity of ≥96.0% (GC). This product is suitable for research and technical applications; TSS does not represent it as USP, BP, EP, or pharmacopoeia grade.
What are the safety considerations when handling N-Boc-ethanolamine?
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N-Boc-ethanolamine is a hazardous substance. It is toxic if swallowed (H301), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, must be worn, and handling should occur in a well-ventilated area. Always consult the Safety Data Sheet (SDS) before use.
How is N-Boc-ethanolamine packed and shipped?
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N-Boc-ethanolamine is packed and shipped according to international regulations for hazardous materials. UN 2810, Class 6.1, Packing Group III applies. TSS, as a global supplier and exporter, ensures compliance with all relevant shipping and customs requirements.
How can I request a quote or sample for N-Boc-ethanolamine?
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To request a quote or sample of N-Boc-ethanolamine, please contact our sales department via the website or your dedicated account manager. Please provide your contact details and the quantity required.
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