N-Boc-aniline
N-Boc-aniline (CAS: 3422-01-3), also known as tert-Butyl-N-phenylcarbamate, is a valuable organic building block with the linear formula C<sub>6</sub>H<sub>5</sub>NHCO<sub>2</sub>C(CH<sub>3</sub>)<sub>3</sub> and a molecular weight of 193.24 g/mol. This protected amine derivative is widely employed in organic synthesis for the controlled introduction of aniline moieties. Its primary utility lies in its ability to facilitate complex molecule construction across various chemical research and development sectors.
- IUPAC
- tert-Butyl-N-phenylcarbamate
- Synonyms
- tert-Butyl N-phenylcarbamateN-(tert-Butoxycarbonyl)aniline
Organic Synthesis Intermediate
N-Boc-aniline serves as a crucial intermediate in multi-step organic syntheses. The Boc protecting group allows for selective functionalization of other parts of a molecule before deprotection to reveal the free amine.
Pharmaceutical Research
It is utilised in the development of novel pharmaceutical compounds, acting as a building block for active pharmaceutical ingredients (APIs). Its protected nature is advantageous in intricate synthetic routes common in drug discovery.
Material Science
This compound can be incorporated into the synthesis of specialized polymers and materials where an aniline unit is required. The Boc protection offers a pathway for controlled polymerisation or post-polymerisation modification.
| Molecular weight | 193.24 |
|---|---|
| Linear formula | C6H5NHCO2C(CH3)3 |
| Assay | 97% |
| Melting point | 133-137 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-aniline used for?
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N-Boc-aniline is primarily used as a protected amine building block in organic synthesis, particularly in the pharmaceutical and material science industries, for constructing complex molecules.
What is the CAS number and molecular formula for N-Boc-aniline?
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The CAS number for N-Boc-aniline is 3422-01-3, and its linear formula is C<sub>6</sub>H<sub>5</sub>NHCO<sub>2</sub>C(CH<sub>3</sub>)<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-aniline with a minimum assay of 97%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should N-Boc-aniline be handled?
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Handle N-Boc-aniline with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Consult the Safety Data Sheet (SDS) for comprehensive handling information.
Is N-Boc-aniline a controlled substance?
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Based on the provided data, N-Boc-aniline is not listed as a controlled substance. However, users should always verify local regulations.
How is N-Boc-aniline packed and shipped?
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N-Boc-aniline is carefully packaged to ensure stability during transit and is available for global export by Tech Serve Solutions.
How can I request a quote or sample of N-Boc-aniline?
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To request a quote or sample of N-Boc-aniline, please contact the Tech Serve Solutions sales team through our official channels.
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