N-Boc-L-phenylalaninal
N-Boc-L-phenylalaninal (CAS: 72155-45-4) is a chiral aldehyde derivative of L-phenylalanine, protected with a tert-butoxycarbonyl (Boc) group. This compound serves as a crucial intermediate in organic synthesis, particularly for creating complex molecules with specific stereochemistry. Its structure makes it valuable in the development of pharmaceutical agents, including enzyme inhibitors.
- IUPAC
- (S)-(−)-2-(tert-Butoxycarbonylamino)-3-phenylpropanal
- Synonyms
- (S)-(−)-2-(tert-Butoxycarbonylamino)-3-phenylpropanal
![N-Boc-L-phenylalaninal (C6H5CH2CH[NHCO2C(CH3)3]CHO) — chemical structure, CAS 72155-45-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F72155-45-4.png&w=3840&q=75)
Synthesis of Enzyme Inhibitors
N-Boc-L-phenylalaninal is a key intermediate in the synthesis of hydroxyethylene dipeptide isosteres. These isosteres are designed to inhibit enzymes, making them valuable in pharmaceutical research and development, particularly for antiviral therapies.
Chiral Building Block
As a chiral aldehyde, this compound is a versatile building block in asymmetric synthesis. It allows for the stereoselective construction of complex organic molecules, enabling the creation of enantiomerically pure target compounds.
Peptidomimetics
The compound is utilized in the design and synthesis of peptidomimetics, which are molecules that mimic the structure and function of peptides. This is important for developing drugs that target peptide-protein interactions.
| Molecular weight | 249.31 |
|---|---|
| Linear formula | C6H5CH2CH[NHCO2C(CH3)3]CHO |
| Assay | 97% |
| Optical activity | [α]20/D −47°, c = 0.5 in methanol |
| Storage temperature | −20°C |
| Application | Intermediate for the synthesis of hydroxyethylene dipeptide isosteres that have enzyme inhibition properties.1 |
| Melting point | 86-88 °C(lit.) |
| Gene Information | human ... CTSK(1513) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-L-phenylalaninal used for?
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N-Boc-L-phenylalaninal is primarily used as an intermediate in the synthesis of hydroxyethylene dipeptide isosteres, which possess enzyme inhibition properties, and as a chiral building block in asymmetric organic synthesis.
What is the CAS number and formula for N-Boc-L-phenylalaninal?
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The CAS number for N-Boc-L-phenylalaninal is 72155-45-4. Its linear formula is C 6 H 5 CH 2 CH[NHCO 2 C(CH 3 ) 3 ]CHO, and its molecular weight is 249.31 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-L-phenylalaninal with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for N-Boc-L-phenylalaninal?
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N-Boc-L-phenylalaninal has a WGK Germany rating of 3, indicating it is hazardous to water. It should be handled with appropriate personal protective equipment in a well-ventilated area, and its storage temperature is -20°C.
How is N-Boc-L-phenylalaninal shipped and exported?
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As a global supplier, Tech Serve Solutions exports N-Boc-L-phenylalaninal worldwide. Specific shipping and handling details are provided upon order confirmation to comply with all relevant regulations.
How can I request a quote or sample for N-Boc-L-phenylalaninal?
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To request a quote or a sample of N-Boc-L-phenylalaninal, please contact our sales team through the website or by phone, providing your specific requirements.
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