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[4-(4-Morpholinylmethyl)phenyl]magnesium bromide solution

CAS 480424-75-7C6H4CH2NOC4H8MgBrChemical Synthesis

[4-(4-Morpholinylmethyl)phenyl]magnesium bromide solution (CAS 480424-75-7) is an organometallic reagent featuring a Grignard functionality. Its linear formula is C<sub>6</sub>H<sub>4</sub>CH<sub>2</sub>NOC<sub>4</sub>H<sub>8</sub>MgBr, with a molecular weight of 280.44 g/mol. Supplied as a 0.25 M solution in THF, this compound is primarily utilised in synthetic organic chemistry as a versatile building block for introducing the 4-(morpholinylmethyl)phenyl group into target molecules, particularly in the development of novel pharmaceutical compounds.

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[4-(4-Morpholinylmethyl)phenyl]magnesium bromide solution (C6H4CH2NOC4H8MgBr) — chemical structure, CAS 480424-75-7; Chemistry, fine chemical supplied by Tech Serve Solutions
ArylChemical SynthesisGrignard ReagentsOrganometallic Reagents
01 /Applications

Organic Synthesis

Serves as a crucial Grignard reagent for carbon-carbon bond formation, enabling the synthesis of complex organic molecules. It is instrumental in introducing the 4-(morpholinylmethyl)phenyl moiety into diverse chemical structures.

Pharmaceutical Intermediates

Utilised in the multi-step synthesis of potential drug candidates and active pharmaceutical ingredients. Its structure lends itself to incorporation into molecules with desired biological activities.

Material Science

Can be employed in the development of novel materials where the specific aryl-morpholine structure is beneficial for tuning material properties.

02 /Properties
Molecular weight280.44
Linear formulaC6H4CH2NOC4H8MgBr
Boiling point65 °C
Density0.926 g/mL at 25 °C
Concentration0.25 M in THF
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
Danger

Hazard statements

  • H225Highly flammable liquid and vapour
  • H314Causes severe skin burns and eye damage
  • H335May cause respiratory irritation
  • H351Suspected of causing cancer

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Flash point-17 °C / 1.4 °F
Transport (UN / ADR)UN 2924 8(3) / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,Xn
Risk statements (R)11-14-19-36/37/38-40
Safety statements (S)16-26-36/37
Supplemental hazardsMay form explosive peroxides., Reacts violently with water.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
480424-75-7
MDL number
MFCD03840890
PubChem substance
24880610
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is [4-(4-Morpholinylmethyl)phenyl]magnesium bromide solution used for?

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[4-(4-Morpholinylmethyl)phenyl]magnesium bromide solution is used in organic synthesis for carbon-carbon bond formation, particularly for introducing the 4-(morpholinylmethyl)phenyl group in the development of pharmaceutical intermediates and novel materials.

What are the CAS number and formula for this compound?

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The CAS number is 480424-75-7, and the linear formula is C<sub>6</sub>H<sub>4</sub>CH<sub>2</sub>NOC<sub>4</sub>H<sub>8</sub>MgBr.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this compound as a 0.25 M solution in THF. We do not represent it as USP, BP, or EP grade.

How should [4-(4-Morpholinylmethyl)phenyl]magnesium bromide solution be handled?

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This compound is flammable and corrosive, and may form explosive peroxides. Handle with extreme care in a well-ventilated area, away from ignition sources, and avoid contact with water. Refer to the Safety Data Sheet (SDS) for detailed handling procedures.

How is this product shipped?

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This product is classified as UN 2924, Hazard Class 8(3), Packing Group II, indicating it is a corrosive and flammable liquid, a combination, packing group II. It is shipped accordingly by expert logistics partners.

How can I request a sample or quote?

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To request a sample or a quote, please contact our sales team through the Tech Serve Solutions website or by calling our dedicated customer service line.

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