1,4-Bis(3-aminopropyl)piperazine
1,4-Bis(3-aminopropyl)piperazine (CAS: 7209-38-3), with the molecular formula C10H24N4 and a molecular weight of 200.32 g/mol, is a versatile chemical building block. It is characterised by its piperazine ring substituted with two aminopropyl chains. This compound is primarily employed in chemical synthesis and research applications, serving as a key intermediate in the development of more complex molecules and materials. Its structure lends itself to various functionalisation processes.
- Synonyms
- 1,4-Piperazinedipropanamine3,3'-(Piperazine-1,4-diyl)dipropylamine

Chemical Synthesis Intermediate
1,4-Bis(3-aminopropyl)piperazine acts as a difunctional building block in organic synthesis. Its primary amine groups allow for reactions such as acylation, alkylation, and condensation, enabling the construction of polymers, ligands, and other complex organic structures.
Material Science Research
This compound has been utilised to functionalise materials such as natural montmorillonite and synthetic kanemite. Such functionalisation can alter the surface properties and reactivity of the base materials for specific applications in areas like adsorption or catalysis.
Pharmaceutical and Agrochemical Intermediate
The piperazine core and amine functionalities make 1,4-Bis(3-aminopropyl)piperazine a potential scaffold for the synthesis of biologically active compounds. It may serve as an intermediate in the development of new pharmaceutical agents or agrochemicals.
| Molecular weight | 200.32 |
|---|---|
| Empirical formula | C10H24N4 |
| Assay | ≥99% |
| Boiling point | 150-152 °C/2 mmHg(lit.) |
| Density | 0.973 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.502(lit.) |
| Vapour density | 6.9 (vs air) |
| Melting point | 15 °C(lit.) |
| Application | 1,4-Bis(3-aminopropyl)piperazine was used to functionalize natural montmorillonite (M) and synthetic kanemite (K)1. |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 163 °C / 325.4 °F |
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Grin2a(24409) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,4-Bis(3-aminopropyl)piperazine used for?
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1,4-Bis(3-aminopropyl)piperazine is used as a building block in chemical synthesis, for functionalising materials like clays, and as an intermediate in the research and development of potential pharmaceutical and agrochemical compounds.
What is the CAS number and molecular formula for 1,4-Bis(3-aminopropyl)piperazine?
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The CAS number is 7209-38-3, and the molecular formula is C10H24N4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,4-Bis(3-aminopropyl)piperazine with an assay of ≥99%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 1,4-Bis(3-aminopropyl)piperazine be handled safely?
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1,4-Bis(3-aminopropyl)piperazine is classified as corrosive. Handle with appropriate personal protective equipment, including gloves, eye protection (goggles and face shield), and respiratory protection. Ensure adequate ventilation. Refer to the safety data sheet for comprehensive handling instructions.
How is 1,4-Bis(3-aminopropyl)piperazine packed, shipped, and exported?
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Tech Serve Solutions ensures appropriate packaging for safe transport and export of 1,4-Bis(3-aminopropyl)piperazine, adhering to international shipping regulations. Specific packaging details can be provided upon request.
How can I request a quote or sample for 1,4-Bis(3-aminopropyl)piperazine?
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To request a quote or sample, please contact our sales team through the website or by phone. Provide your contact details and the quantity required.
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