1,4-Bis(acryloyl)piperazine
1,4-Bis(acryloyl)piperazine (CAS: 6342-17-2) is a chemical compound with the molecular formula C10H14N2O2 and a molecular weight of 194.23 g/mol. It serves as a valuable building block in chemical synthesis and is particularly noted for its utility as a gel cross-linker. This compound is also recognised for its suitability in electrophoresis applications, including gel casting and protein analysis.
- IUPAC
- 1,4-Di(acryloyl)piperazine,N,N′-Bis(acryloyl)piperazine,BAP,PDA,Piperazine diacrylamide
- Synonyms
- 1,4-Di(acryloyl)piperazineN,N′-Bis(acryloyl)piperazineBAPPDAPiperazine diacrylamide

Chemical Synthesis
1,4-Bis(acryloyl)piperazine functions as a versatile building block in organic synthesis. Its reactive acryloyl groups allow for various chemical transformations, contributing to the creation of complex molecular structures.
Gel Casting and Cross-linking
This compound is employed as a cross-linking agent in the preparation of polyacrylamide gels. Its ability to form stable cross-links is crucial for controlling gel properties in electrophoresis and other biochemical applications.
Electrophoresis Applications
With demonstrated suitability for electrophoresis, 1,4-Bis(acryloyl)piperazine is used in techniques such as SDS-PAGE. It aids in the precise separation of biomolecules based on size and charge.
Material Science
The difunctional nature of 1,4-Bis(acryloyl)piperazine makes it a potential monomer or cross-linker in the development of novel polymers and advanced materials with tailored properties.
| Molecular weight | 194.23 |
|---|---|
| Empirical formula | C10H14N2O2 |
| Assay | ≥99.0% (TLC) |
| Storage temperature | 2-8°C |
| Impurities tested | ≤0.05% free acrylic acid |
| Suitability | suitable for electrophoresis |
| Melting point | 91.5-93.5 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
| Cation traces | Ca: ≤10 mg/kgCd: ≤5 mg/kgCo: ≤5 mg/kgCr: ≤5 mg/kgCu: ≤5 mg/kgFe: ≤5 mg/kgK: ≤50 mg/kgMg: ≤5 mg/kgMn: ≤5 mg/kgNa: ≤50 mg/kgNi: ≤5 mg/kgPb: ≤5 mg/kgZn: ≤5 mg/kg |
| Anion traces | chloride (Cl-): ≤200 mg/kgsulfate (SO42-): ≤50 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioXtra |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,4-Bis(acryloyl)piperazine used for?
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1,4-Bis(acryloyl)piperazine is used as a building block in chemical synthesis, a gel cross-linker, and in electrophoresis applications like SDS-PAGE.
What is the CAS number and formula for 1,4-Bis(acryloyl)piperazine?
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The CAS number is 6342-17-2, and the empirical formula (Hill notation) is C10H14N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,4-Bis(acryloyl)piperazine with an assay of ≥99.0% (TLC) and contains ≤0.05% free acrylic acid. It is suitable for electrophoresis. It is not represented as USP, BP, or EP grade.
How should 1,4-Bis(acryloyl)piperazine be handled safely?
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1,4-Bis(acryloyl)piperazine is a Warning substance (GHS07) that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Use a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. In case of contact with eyes, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. Continue rinsing.
How is 1,4-Bis(acryloyl)piperazine packaged and exported?
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1,4-Bis(acryloyl)piperazine is stored at 2-8°C. Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals, capable of handling international shipments.
How can I request a sample or quote for 1,4-Bis(acryloyl)piperazine?
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Please contact Tech Serve Solutions directly via our website or sales channels to request a sample or a quotation for 1,4-Bis(acryloyl)piperazine.
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