2-Amino-5-iodopyrimidine
2-Amino-5-iodopyrimidine (CAS: 1445-39-2), with the molecular formula C4H4IN3 and a molecular weight of 221.00 g/mol, is a halogenated heterocyclic building block. This compound is primarily utilised in chemical synthesis, serving as a key intermediate in the development of more complex organic molecules. Its specific structural features, particularly the amino and iodo groups on the pyrimidine ring, make it a versatile reagent in various synthetic pathways.

Organic Synthesis Intermediate
2-Amino-5-iodopyrimidine is employed as a fundamental building block in organic synthesis. It is valuable for introducing the pyrimidine moiety into larger molecular structures, often found in medicinal chemistry research.
Pharmaceutical Research
This compound serves as an intermediate in the synthesis of potential pharmaceutical agents. The iodo-substituent allows for further functionalisation via cross-coupling reactions, enabling the creation of diverse chemical libraries.
Heterocyclic Chemistry
As a functionalised pyrimidine, it is a useful reagent for researchers working with heterocyclic compounds. Its reactivity enables the construction of novel heterocyclic systems with potential biological activity.
| Molecular weight | 221.00 |
|---|---|
| Empirical formula | C4H4IN3 |
| Assay | 97% |
| Melting point | 218-223 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-5-iodopyrimidine used for?
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2-Amino-5-iodopyrimidine is used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and heterocyclic chemistry for creating more complex molecules.
What is the CAS number and molecular formula for 2-Amino-5-iodopyrimidine?
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The CAS number is 1445-39-2 and the molecular formula is C4H4IN3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-5-iodopyrimidine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Amino-5-iodopyrimidine be handled safely?
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Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. Avoid dust formation and inhalation, skin contact, and eye contact. Ensure good ventilation. This compound is classified as Danger with hazards including H302, H315, H318, and H335.
Is 2-Amino-5-iodopyrimidine shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Amino-5-iodopyrimidine.
How can I request a sample or quote for 2-Amino-5-iodopyrimidine?
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To request a sample or quote, please contact our sales team through the website or by phone, providing your contact details and the quantity required.
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