2-Amino-5-iodo-3-nitropyridine
2-Amino-5-iodo-3-nitropyridine (CAS: 25391-57-5; C5H4IN3O2) is a halogenated pyridine derivative. This compound serves as a valuable building block in organic synthesis, particularly for the construction of more complex heterocyclic molecules. Its structure, featuring an amino group, an iodine atom, and a nitro group on a pyridine ring, offers multiple reactive sites for further chemical transformations. It is typically used in research and development settings.

Organic Synthesis Intermediate
This compound is employed as a key intermediate in the synthesis of various organic molecules. The presence of the iodine atom allows for cross-coupling reactions, while the amino and nitro groups can be further functionalised.
Heterocyclic Chemistry
As a functionalised pyridine, it is a useful building block in heterocyclic chemistry. It can be incorporated into larger ring systems or used to create novel pyridine-based compounds with potential pharmaceutical or material science applications.
Research and Development
2-Amino-5-iodo-3-nitropyridine is utilised in academic and industrial research laboratories for exploring new synthetic routes and developing novel chemical entities.
| Molecular weight | 265.01 |
|---|---|
| Empirical formula | C5H4IN3O2 |
| Assay | 97% |
| Melting point | 215-219 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-5-iodo-3-nitropyridine used for?
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2-Amino-5-iodo-3-nitropyridine is primarily used as a building block in organic synthesis and heterocyclic chemistry for research and development purposes.
What is the CAS number and chemical formula for 2-Amino-5-iodo-3-nitropyridine?
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The CAS number is 25391-57-5 and the chemical formula is C5H4IN3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-5-iodo-3-nitropyridine with an assay of 97%. This product is not represented as USP, BP, EP or other pharmacopoeia grades.
How should 2-Amino-5-iodo-3-nitropyridine be handled?
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2-Amino-5-iodo-3-nitropyridine is a Warning substance that may cause gastrointestinal irritation if swallowed (H302), skin irritation (H315), allergic skin reaction (H317), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment including a dust mask (type N95 or equivalent), eyeshields, faceshields, and gloves should be worn. Handle in a well-ventilated area.
How is 2-Amino-5-iodo-3-nitropyridine packed and exported?
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Tech Serve Solutions packs and exports chemicals according to international regulations for safe transport, ensuring product integrity during shipping.
How can I request a sample or quote for 2-Amino-5-iodo-3-nitropyridine?
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To request a sample or quote for 2-Amino-5-iodo-3-nitropyridine, please contact the Tech Serve Solutions sales team through our website or by phone.
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