2-Bromo-3-methylbutyric acid
2-Bromo-3-methylbutyric acid (CAS 565-74-2) is an organic compound with the linear formula (CH3)2CHCHBrCOOH and a molecular weight of 181.03 g/mol. This carboxylic acid derivative serves as a valuable building block in organic synthesis. It is primarily utilised in the preparation of more complex molecules, notably in the field of chiral chemistry for the synthesis of specific amino acid derivatives.
- IUPAC
- α-Bromoisovaleric acid,2-Bromoisovaleric acid
- Synonyms
- α-Bromoisovaleric acid2-Bromoisovaleric acid
Chiral Synthesis Intermediate
2-Bromo-3-methylbutyric acid is employed as a precursor in the synthesis of optically active compounds. Its structure allows for stereoselective transformations, making it useful in the preparation of specific enantiomers of amino acids and other chiral molecules.
Organic Building Block
As a functionalised carboxylic acid containing a bromine atom, this compound offers versatile reactivity for various organic transformations. It can participate in nucleophilic substitution reactions or serve as a starting point for further functional group manipulations in multi-step syntheses.
Research and Development
This chemical is utilised in academic and industrial research laboratories for exploring new synthetic routes and developing novel chemical entities. Its availability supports fundamental research in organic chemistry and medicinal chemistry.
| Molecular weight | 181.03 |
|---|---|
| Linear formula | (CH3)2CHCHBrCOOH |
| Assay | 97% |
| Boiling point | 124-126 °C/20 mmHg(lit.) |
| Solubility | alcohol: soluble(lit.)diethyl ether: soluble(lit.)water: very slightly soluble(lit.) |
| Application | 2-Bromo-3-methylbutyric acid has been used in the preparation of optically active N-methylvalines1. |
| Melting point | 39-42 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 21/22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-3-methylbutyric acid used for?
+
2-Bromo-3-methylbutyric acid is primarily used as a building block in organic synthesis, particularly for the preparation of optically active N-methylvalines and other chiral compounds. It serves as a valuable intermediate in research and development for creating novel chemical entities.
What is the CAS number and chemical formula for 2-Bromo-3-methylbutyric acid?
+
The CAS number for 2-Bromo-3-methylbutyric acid is 565-74-2, and its linear formula is (CH3)2CHCHBrCOOH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Bromo-3-methylbutyric acid with a minimum assay of 97%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Bromo-3-methylbutyric acid be handled safely?
+
2-Bromo-3-methylbutyric acid is classified as Danger, with hazards including H302 (Harmful if swallowed), H312 (Harmful in contact with skin), and H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, must be used. Handle in a well-ventilated area.
How is 2-Bromo-3-methylbutyric acid packed, shipped, and exported?
+
2-Bromo-3-methylbutyric acid is packed in compliance with international shipping regulations for hazardous materials. It is typically shipped as UN 3261, Class 8, Packing Group II. TSS offers global export services for this chemical.
How can I request a quote or sample for 2-Bromo-3-methylbutyric acid?
+
To request a quote or a sample of 2-Bromo-3-methylbutyric acid, please contact the TSS sales department via the website or by phone. Provide your contact details and the quantity required.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis