Diisopropylzinc solution
Diisopropylzinc solution (CAS: 625-81-0, Formula: Zn(CH(CH3)2)2, MW: 151.57) is a highly reactive organometallic reagent. Supplied as a 1.0 M solution in toluene, it exhibits a low flash point of -5 °C and requires careful handling under inert conditions due to its pyrophoric nature and reactivity with water. This compound is a valuable tool in organic synthesis for introducing isopropyl groups and in the preparation of other organozinc reagents.
Organozinc Reagent Synthesis
Diisopropylzinc is used in the preparation of other more complex organozinc compounds. It serves as a precursor in various metal-mediated coupling reactions, facilitating carbon-carbon bond formation.
Catalysis
In organometallic chemistry, dialkylzincs like diisopropylzinc can function as co-catalysts or active components in catalytic systems. They are employed in polymerisation reactions and asymmetric synthesis.
Organic Synthesis
This reagent is employed in organic synthesis for the nucleophilic addition to carbonyl compounds and other electrophiles. It is particularly useful for the stereoselective synthesis of chiral alcohols and other complex organic molecules.
| Molecular weight | 151.57 |
|---|---|
| Linear formula | Zn(CH(CH3)2)2 |
| Density | 0.895 g/mL at 25 °C |
| Concentration | 1.0 M in toluene |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H250Catches fire spontaneously if exposed to air
- H261In contact with water releases flammable gas
- H304May be fatal if swallowed and enters airways
- H314Causes severe skin burns and eye damage
- H336May cause drowsiness or dizziness
- H361D
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P222Do not allow contact with air
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P422
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -5 °C / 23 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 63-11-14-17-34-48/20-65-67 |
| Safety statements (S) | 16-26-36/37/39-45-62 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diisopropylzinc solution used for?
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Diisopropylzinc solution is primarily used in organic synthesis for introducing isopropyl groups, in the preparation of other organozinc reagents, and in catalytic applications such as polymerisation and asymmetric synthesis.
What is the CAS number and formula for Diisopropylzinc solution?
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The CAS number for Diisopropylzinc solution is 625-81-0, and its chemical formula is Zn(CH(CH3)2)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diisopropylzinc solution at a concentration of 1.0 M in toluene. We do not specify a grade or purity beyond what is listed, and it is not represented as USP/BP/EP.
How should Diisopropylzinc solution be handled safely?
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Diisopropylzinc solution is highly flammable and pyrophoric, reacting violently with water. It must be handled under an inert atmosphere (e.g., nitrogen or argon) using appropriate personal protective equipment, including eyeshields, face shields, and suitable gloves. Storage is recommended at 2-8°C.
How is Diisopropylzinc solution shipped and exported?
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Diisopropylzinc solution is shipped and exported as a hazardous material under UN 3399, Class 4.3, Packing Group II, requiring specialised packaging and adherence to strict transport regulations for flammable solids or substances liable to spontaneous combustion.
How can I request a sample or quote for Diisopropylzinc solution?
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To request a sample or a quote for Diisopropylzinc solution, please contact our sales team through the website or by phone, providing your contact details and the quantity required.
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