Diketene
Diketene (CAS: 674-82-8), with the molecular formula C4H4O2 and a molecular weight of 84.07 g/mol, is a reactive organic compound. This colourless liquid is primarily utilised as a versatile intermediate in the synthesis of various acetoacetic acid derivatives and heterocyclic compounds. Its characteristic reactivity makes it a valuable building block in organic synthesis for industrial and research applications.
Synthesis of Acetoacetic Acid Derivatives
Diketene serves as a key reagent for the preparation of acetoacetic esters and amides. These derivatives are important intermediates in the synthesis of pharmaceuticals, agrochemicals, and dyes.
Heterocyclic Compound Formation
It is extensively employed in the construction of various heterocyclic ring systems. Its reactivity allows for the facile introduction of the acetoacetyl group into complex molecular structures.
Organic Synthesis Building Block
As a fundamental organic building block, diketene enables the efficient creation of more complex molecules. It is widely used in laboratory research and industrial chemical manufacturing processes.
| Molecular weight | 84.07 |
|---|---|
| Empirical formula | C4H4O2 |
| Boiling point | 69-70 °C/100 mmHg(lit.) |
| Density | 1.09 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.439(lit.) |
| Vapour pressure | 7.9 mmHg (20 °C) |
| Vapour density | 2.9 (vs air) |
| Autoignition temp | 590 °F |
| Contains / stabiliser | copper sulfate as stabilizer |
| Application | Employed in the convenient preparation of acetoacetic acid derivatives and heterocycles.1 |
Hazard statements
- H226Flammable liquid and vapour
- H332Harmful if inhaled
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 34 °C / 93.2 °F |
| Transport (UN / ADR) | UN 2521 3(6.1) / PGI |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20 |
| Safety statements (S) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diketene used for?
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Diketene is used in the convenient preparation of acetoacetic acid derivatives and heterocycles, serving as a valuable building block in organic synthesis.
What is the CAS number and formula for Diketene?
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The CAS number for Diketene is 674-82-8, and its molecular formula is C4H4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diketene typically as a technical or research grade chemical. TSS does not represent this product as USP, BP, or EP grade.
How should Diketene be handled safely?
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Diketene is a flammable liquid and vapour (H226) and harmful if inhaled (H332). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Store away from heat and ignition sources.
How is Diketene packed, shipped, and exported?
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Diketene is carefully packed in UN-approved containers suitable for flammable liquids. Tech Serve Solutions is experienced in exporting this chemical globally, adhering to all relevant shipping regulations.
How can I request a quote or sample of Diketene?
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To request a quote or a sample of Diketene, please contact our sales department with your specific requirements.
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