Diisopropylsilyl bis(trifluoromethanesulfonate)
Diisopropylsilyl bis(trifluoromethanesulfonate) (CAS 85272-30-6) is a silicon-based chemical reagent with the linear formula (CF3SO3)2Si[CH(CH3)2]2 and a molecular weight of 412.40 g/mol. It serves as a valuable tool in organic synthesis, particularly for protection and derivatization reactions. Its efficacy lies in its ability to introduce the diisopropylsilyl group, a robust protecting group for various functional moieties in complex molecular structures.
- IUPAC
- Trifluoromethanesulfonic acid diisopropylsilylene ester
- Synonyms
- Trifluoromethanesulfonic acid diisopropylsilylene ester
![Diisopropylsilyl bis(trifluoromethanesulfonate) ((CF3SO3)2Si[CH(CH3)2]2) — chemical structure, CAS 85272-30-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F85272-30-6.png&w=3840&q=75)
Protecting Group Chemistry
Diisopropylsilyl bis(trifluoromethanesulfonate) is employed to install the diisopropylsilyl (DIPS) protecting group onto hydroxyl and other nucleophilic functionalities. This protection is often utilized in multi-step syntheses where selective manipulation of other parts of a molecule is required.
Derivatization Reagent
This compound can be used to derivatize molecules, facilitating their analysis or purification. The introduction of the silyl group can alter chromatographic properties or enhance volatility for techniques like gas chromatography.
Organic Synthesis
As a versatile reagent in chemical synthesis, it enables the formation of silicon-containing compounds and intermediates. Its reactivity profile makes it suitable for various synthetic transformations in research and development settings.
| Molecular weight | 412.40 |
|---|---|
| Linear formula | (CF3SO3)2Si[CH(CH3)2]2 |
| Assay | ≥97.0% (T) |
| Boiling point | 85-86 °C/2 mmHg(lit.) |
| Density | 1.396 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.382(lit.)n20/D 1.382 |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diisopropylsilyl bis(trifluoromethanesulfonate) used for?
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Diisopropylsilyl bis(trifluoromethanesulfonate) is primarily used as a reagent in organic synthesis for introducing the diisopropylsilyl protecting group, particularly onto hydroxyl functionalities in complex molecules.
What is the CAS number and chemical formula for Diisopropylsilyl bis(trifluoromethanesulfonate)?
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The CAS number is 85272-30-6 and the linear formula is (CF3SO3)2Si[CH(CH3)2]2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diisopropylsilyl bis(trifluoromethanesulfonate) with an assay of ≥97.0% (T). We do not represent this product as USP, BP, EP or other pharmacopoeial grades.
How should Diisopropylsilyl bis(trifluoromethanesulfonate) be handled safely?
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This compound is corrosive and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, goggles, and face shields, should be worn. Work in a well-ventilated area or use a suitable respirator. Refer to the Safety Data Sheet for comprehensive handling information.
Is Diisopropylsilyl bis(trifluoromethanesulfonate) a controlled substance?
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There is no information in the provided data to suggest that Diisopropylsilyl bis(trifluoromethanesulfonate) is a controlled substance.
How is Diisopropylsilyl bis(trifluoromethanesulfonate) packed and shipped?
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Diisopropylsilyl bis(trifluoromethanesulfonate) is shipped under UN 3265, Class 8, Packing Group II regulations, indicating it is a corrosive liquid, acidic, organic, n.o.s. Packing is compliant with international shipping standards.
How can I request a sample or quote for Diisopropylsilyl bis(trifluoromethanesulfonate)?
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To request a sample or a quotation for Diisopropylsilyl bis(trifluoromethanesulfonate), please contact our sales department through the website or by phone, providing your specific requirements.
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