5′-Fluoro-2′-methoxyacetophenone
5′-Fluoro-2′-methoxyacetophenone (CAS: 445-82-9), a fluorinated organic compound with the molecular formula C9H9FO2 and a molecular weight of 168.16 g/mol, serves as a valuable building block in organic synthesis. This ketone derivative is characterised by its fluorine and methoxy substituents, making it useful in the development of novel chemical entities. It is frequently employed in research and development settings for the construction of more complex molecules.
- IUPAC
- 1-(5-Fluoro-2-methoxyphenyl)ethanone

Organic Synthesis Intermediate
This compound is a versatile intermediate for the synthesis of diverse organic molecules. Its structure allows for various chemical transformations, making it a useful component in multi-step synthetic pathways.
Pharmaceutical Research
As a fluorinated building block, 5′-Fluoro-2′-methoxyacetophenone can be incorporated into potential drug candidates. Fluorine atoms often influence a molecule's pharmacokinetic and pharmacodynamic properties.
Material Science Exploration
The unique electronic properties imparted by the fluorine atom may find application in the development of new materials. Researchers may utilise this compound in exploratory studies for novel functional materials.
| Molecular weight | 168.16 |
|---|---|
| Empirical formula | C9H9FO2 |
| Assay | 97% |
| Density | 1.1880 g/mL at 25 °C |
| Refractive index | n20/D 1.5186 |


Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5′-Fluoro-2′-methoxyacetophenone primarily used for?
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5′-Fluoro-2′-methoxyacetophenone is primarily used as a building block in organic synthesis, particularly in research and development for creating novel chemical entities, including potential pharmaceutical candidates.
What are the CAS number and molecular formula for 5′-Fluoro-2′-methoxyacetophenone?
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The CAS number for 5′-Fluoro-2′-methoxyacetophenone is 445-82-9, and its molecular formula is C9H9FO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5′-Fluoro-2′-methoxyacetophenone with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 5′-Fluoro-2′-methoxyacetophenone be handled safely?
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Handle with care. This compound is classified as Dangerous, indicated by GHS05 and GHS07 symbols and the signal word 'Danger'. It carries hazard statements H302 (Harmful if swallowed) and H318 (Causes serious eye damage). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Ensure good ventilation and avoid contact with eyes and skin.
Is 5′-Fluoro-2′-methoxyacetophenone packed and exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 5′-Fluoro-2′-methoxyacetophenone, and can arrange for its packaging and export.
How can I request a sample or quote for 5′-Fluoro-2′-methoxyacetophenone?
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To request a sample or a quotation for 5′-Fluoro-2′-methoxyacetophenone, please contact our sales department through the provided contact information on the Tech Serve Solutions website.
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