5′-O-Trityl-2′-deoxy-β-D-lyxofuranosylthymine
5′-O-Trityl-2′-deoxy-β-D-lyxofuranosylthymine (CAS: 55612-11-8; C29H28N2O5) is a crucial modified nucleoside featuring a trityl protecting group on the 5' hydroxyl of the deoxyribose moiety. With a molecular weight of 484.54 g/mol, this compound is essential in organic synthesis, particularly for the preparation of complex oligonucleotides and modified nucleic acid analogues used in biochemical research and drug discovery.

Nucleoside Chemistry
Serves as a protected building block in the synthesis of modified nucleosides and oligonucleotides, facilitating precise chemical modifications.
Oligonucleotide Synthesis
Utilised in solid-phase or solution-phase synthesis to introduce specific structural features into DNA or RNA analogues for research purposes.
Medicinal Chemistry Research
A key intermediate in the exploration and development of novel therapeutic agents, particularly those targeting viral infections or genetic disorders.
Biochemical Probes
Can be incorporated into custom-synthesized nucleic acid probes for diagnostic or research applications in molecular biology.
| Molecular weight | 484.54 |
|---|---|
| Empirical formula | C29H28N2O5 |
| Assay | 98% |
| Optical activity | [α]20/D −39°, c = 0.5 in DMF |
| Melting point | 246-248 °C(lit.) |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Risk statements (R) | 53 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5′-O-Trityl-2′-deoxy-β-D-lyxofuranosylthymine used for?
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This compound is primarily used as a protected building block in organic synthesis, particularly for the preparation of modified nucleosides and oligonucleotides in biochemical research and drug discovery.
What is the CAS number and formula for 5′-O-Trityl-2′-deoxy-β-D-lyxofuranosylthymine?
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The CAS number is 55612-11-8, and the empirical formula is C29H28N2O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 98%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should 5′-O-Trityl-2′-deoxy-β-D-lyxofuranosylthymine be handled safely?
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Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. This compound may cause long-lasting harmful effects to aquatic life (H413).
How is this chemical packed and shipped?
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This chemical is packed and shipped according to standard industry practices for fine chemicals and laboratory reagents, adhering to international shipping regulations for export.
How can I request a sample or quote for 5′-O-Trityl-2′-deoxy-β-D-lyxofuranosylthymine?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
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