5′-Fluoro-2′-hydroxypropiophenone
5′-Fluoro-2′-hydroxypropiophenone (CAS: 443-09-4; Formula: C9H9FO2; MW: 168.16 g/mol) is a fluorinated organic compound. It serves as a valuable building block in organic synthesis, particularly for introducing fluorinated aromatic moieties into more complex molecular structures. Its chemical structure features a propiophenone core with hydroxyl and fluorine substituents, making it suitable for various chemical transformations in research and development settings.

Organic Synthesis Intermediate
This compound acts as a key intermediate in the synthesis of various organic molecules. Its reactive functional groups allow for further chemical modifications in multi-step synthetic pathways.
Pharmaceutical Research
It is utilised in the development of novel pharmaceutical compounds. The presence of fluorine can influence the pharmacokinetic and pharmacodynamic properties of drug candidates.
Material Science
May find application in the synthesis of specialized polymers or functional materials where fluorinated aromatic structures are desired for specific properties like thermal stability or hydrophobicity.
| Molecular weight | 168.16 |
|---|---|
| Empirical formula | C9H9FO2 |
| Assay | 97% |
| Melting point | 35-39 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 103 °C / 217.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5′-Fluoro-2′-hydroxypropiophenone used for?
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5′-Fluoro-2′-hydroxypropiophenone is primarily used as an intermediate in organic synthesis, particularly in pharmaceutical research and potentially in material science for creating fluorinated organic compounds.
What are the CAS number and molecular formula for 5′-Fluoro-2′-hydroxypropiophenone?
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The CAS number is 443-09-4, and the molecular formula is C9H9FO2.
What grade and purity does Tech Serve Solutions supply for 5′-Fluoro-2′-hydroxypropiophenone?
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Tech Serve Solutions supplies 5′-Fluoro-2′-hydroxypropiophenone with an assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 5′-Fluoro-2′-hydroxypropiophenone be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask (N95 recommended), eyeshields, and gloves. It is classified as a Danger hazard, with statements including H302 (Harmful if swallowed), H315 (Causes skin irritation), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). Ensure good ventilation and avoid dust formation.
Is 5′-Fluoro-2′-hydroxypropiophenone a controlled substance?
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The provided data does not indicate that 5′-Fluoro-2′-hydroxypropiophenone is a controlled substance.
How is 5′-Fluoro-2′-hydroxypropiophenone packed and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packing and export details are available upon request.
How can I request a quote or sample for 5′-Fluoro-2′-hydroxypropiophenone?
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To request a quote or sample, please contact the Tech Serve Solutions sales team through the website or provided contact information.
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