D-Pyroglutamic acid ethyl ester
D-Pyroglutamic acid ethyl ester (CAS: 68766-96-1; Formula: C7H11NO3) is a versatile chiral building block with a molecular weight of 157.17 g/mol. This compound is primarily utilised in chemical synthesis, peptide chemistry, and as a derivative in unnatural amino acid research. Its defined optical activity and purity make it a valuable intermediate for producing complex organic molecules and pharmaceuticals. Tech Serve Solutions offers this ester for advanced research and development purposes.
- IUPAC
- (R)-5-Oxoproline ethyl ester,D-5-Oxo-2-pyrrolidinecarboxylic acid ethyl ester

Chemical Synthesis Intermediate
Serves as a chiral synthon in the construction of complex organic molecules. Its defined stereochemistry is crucial for asymmetric synthesis pathways.
Peptide Chemistry
Used in the development and synthesis of modified peptides and peptidomimetics. It can be incorporated into peptide chains to alter their properties.
Unnatural Amino Acid Derivatives
Acts as a precursor for synthesising unnatural amino acids, expanding the scope of available building blocks for drug discovery and biochemical studies.
Chemical Biology Research
Employed in research investigating biological pathways and molecular interactions, leveraging its specific chemical structure.
| Molecular weight | 157.17 |
|---|---|
| Empirical formula | C7H11NO3 |
| Assay | ≥99.0% (sum of enantiomers, HPLC) |
| Boiling point | 176 °C/12 mmHg(lit.) |
| Refractive index | n20/D 1.478(lit.) |
| Optical activity | [α]20/D −4.0±1.0°, c = 10% in ethanol |
| Optical purity | enantiomeric ratio: ≥99:1 (GC) |
| Melting point | 53-57 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Pyroglutamic acid ethyl ester primarily used for?
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D-Pyroglutamic acid ethyl ester is primarily used as an intermediate in chemical synthesis, peptide chemistry, and for the preparation of unnatural amino acid derivatives.
What are the CAS number and chemical formula for D-Pyroglutamic acid ethyl ester?
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The CAS number is 68766-96-1 and the chemical formula is C7H11NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-Pyroglutamic acid ethyl ester with an assay of ≥99.0% (sum of enantiomers, HPLC). This product is not supplied as USP, BP, EP, or any other pharmacopoeial grade and is intended for research and laboratory use.
How should D-Pyroglutamic acid ethyl ester be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a P1 filter respirator if necessary. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
Is D-Pyroglutamic acid ethyl ester a controlled substance?
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The provided data does not indicate that D-Pyroglutamic acid ethyl ester is a controlled substance.
How is D-Pyroglutamic acid ethyl ester shipped or exported?
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D-Pyroglutamic acid ethyl ester is available for global export from Tech Serve Solutions, packaged according to relevant shipping regulations for chemicals.
How can I request a sample or quote for D-Pyroglutamic acid ethyl ester?
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Please contact our sales team via the website or direct email to request a sample or a quotation for D-Pyroglutamic acid ethyl ester.
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