D-Proline methyl ester hydrochloride
D-Proline methyl ester hydrochloride (CAS 65365-28-8), with the molecular formula C6H11NO2 · HCl and a molecular weight of 165.62 g/mol, is a derivative of the amino acid proline. It functions as a key building block in peptide synthesis and is utilised in various chemical biology and organic synthesis applications. This compound is supplied by Tech Serve Solutions, meeting rigorous quality standards for research and development purposes.

Peptide Synthesis
D-Proline methyl ester hydrochloride serves as a crucial chiral building block in the synthesis of peptides and peptidomimetics. Its incorporation allows for the introduction of specific structural motifs and conformational constraints into peptide chains.
Organic Synthesis Intermediate
This compound is employed as an intermediate in the synthesis of complex organic molecules. It provides a versatile proline-based scaffold for the development of novel chemical entities in medicinal chemistry and materials science.
Chemical Biology Research
Utilised in chemical biology, D-Proline methyl ester hydrochloride can be incorporated into probes or modified peptides to investigate biological processes. Its specific stereochemistry is important for molecular recognition studies.
| Molecular weight | 165.62 |
|---|---|
| Empirical formula | C6H11NO2 · HCl |
| Assay | ≥98.0% (AT) |
| Optical activity | [α]/D 33.0±2.0°, c = 1 in H2O |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Proline methyl ester hydrochloride used for?
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D-Proline methyl ester hydrochloride is primarily used as a building block in peptide synthesis and as an intermediate in organic synthesis. It also finds applications in chemical biology research.
What is the CAS number and chemical formula?
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The CAS number for D-Proline methyl ester hydrochloride is 65365-28-8. Its empirical formula is C6H11NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-Proline methyl ester hydrochloride with an assay of ≥98.0% (AT). This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.
How should D-Proline methyl ester hydrochloride be handled?
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Handle D-Proline methyl ester hydrochloride with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. It is a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Avoid breathing dust and ensure adequate ventilation. Store at 2-8°C.
How is this product packed, shipped, and exported?
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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging for stability and compliance with international shipping regulations. Specific packaging details are available upon request.
How can I request a sample or quote?
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To request a sample or a quote for D-Proline methyl ester hydrochloride, please contact the Tech Serve Solutions sales team through our website or by phone, referencing the product CAS number 65365-28-8.
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