D-Prolinamide

CAS 62937-45-5C5H10N2OChemical Synthesis

D-Prolinamide (CAS: 62937-45-5, C5H10N2O) is a chiral pyrrolidine derivative with a molecular weight of 114.15 g/mol. This enantiomerically pure compound serves as a valuable chiral building block in asymmetric synthesis and chemical research. Its specific optical activity, [α]/D +110±3°, highlights its utility in stereoselective reactions, contributing to the creation of complex organic molecules.

IUPAC: (R)-Pyrrolidine-2-carboxamide

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D-Prolinamide (C5H10N2O) — chemical structure, CAS 62937-45-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPyrrolidines

01 /Applications

Chiral Building Block

D-Prolinamide functions as a key chiral synthon in the construction of enantiomerically pure compounds. It is particularly useful in asymmetric synthesis pathways where precise stereochemical control is paramount for the target molecule's properties.

Asymmetric Synthesis

Utilised in stereoselective reactions, this compound enables chemists to introduce specific chirality into molecules. Its pyrrolidine scaffold is frequently incorporated into more complex chiral auxiliaries and ligands used in catalytic processes.

Pharmaceutical Intermediate Development

The chiral nature of D-Prolinamide makes it a sought-after intermediate in the synthesis of active pharmaceutical ingredients (APIs) where stereochemistry dictates biological activity and efficacy.

Heterocyclic Chemistry

As a substituted pyrrolidine, it is employed in the synthesis of novel heterocyclic compounds. These structures are prevalent in medicinal chemistry and materials science research.

02 /Properties

Molecular weight	114.15
Empirical formula	C5H10N2O
Assay	≥99.0% (NT)
Optical activity	[α]/D +110±3°, c = 2 in ethanol
Melting point	101-103 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

62937-45-5

Beilstein registry

471499

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is D-Prolinamide used for?

D-Prolinamide is primarily used as a chiral building block in asymmetric synthesis and chemical research, including the development of pharmaceutical intermediates and novel heterocyclic compounds.

What are the CAS number and formula for D-Prolinamide?

The CAS number for D-Prolinamide is 62937-45-5, and its empirical formula is C5H10N2O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies D-Prolinamide with an assay of ≥99.0% (NT). TSS does not represent this product as USP/BP/EP grade.

What safety precautions should be taken when handling D-Prolinamide?

When handling D-Prolinamide, it is essential to use personal protective equipment such as eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. The compound is classified under WGK 2 in Germany, indicating it is hazardous to water.

How is D-Prolinamide packed, shipped, and exported?

Tech Serve Solutions professionally packs and exports fine chemicals like D-Prolinamide globally, adhering to all relevant shipping regulations for chemical substances.

How can I request a sample or quote for D-Prolinamide?

To request a sample or quote for D-Prolinamide, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.