22(S)-Hydroxycholesterol

CAS 22348-64-7C27H46O2Biochemicals & Reagents

22(S)-Hydroxycholesterol (CAS: 22348-64-7) is a sterol derivative with the molecular formula C27H46O2. This compound is primarily utilized in biochemical research, particularly for studying cholesterol metabolism and its modulation within cellular pathways. Its structural similarity to cholesterol makes it a valuable tool for investigating steroid hormone synthesis and related biological processes.

IUPAC: 22β-Hydroxycholesterol,5-Cholestene-3β,22(S)-diol

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22(S)-Hydroxycholesterol (C27H46O2) — chemical structure, CAS 22348-64-7; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsCell BiologyCholesterol and DerivativesLipidsMetabolic PathwaysMetabolomicsSteroid MetabolismSterol Lipids More...

01 /Applications

Cholesterol Modulation Studies

Human hepatoma cells have been treated with 22(S)-Hydroxycholesterol to investigate cholesterol regulation mechanisms. These studies focus on how liver X receptor-mediated gene expression influences cholesterol homeostasis.

Biochemical Research

As a cholesterol derivative, 22(S)-Hydroxycholesterol serves as a crucial reagent in laboratories exploring lipid metabolism and steroid biochemistry. It aids in understanding complex metabolic pathways.

Cell Biology Investigations

This compound is employed in cell biology to probe the intricate roles of sterols within cellular functions. Its application helps elucidate mechanisms related to cell membrane integrity and signaling.

02 /Properties

Molecular weight	402.65
Empirical formula	C27H46O2
Application	Human hepatoma cells were treated with 22(S)-Hydroxycholesterol to study cholesterol modulation by liver X receptor-mediated gene regulation.1

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

22348-64-7

MDL number

MFCD00010476

PubChem substance

24895715

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 22(S)-Hydroxycholesterol used for?

22(S)-Hydroxycholesterol is used in biochemical research, particularly for studying cholesterol modulation, liver X receptor-mediated gene regulation, and lipid metabolism.

What is the CAS number and molecular formula for 22(S)-Hydroxycholesterol?

The CAS number is 22348-64-7 and the molecular formula is C27H46O2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 22(S)-Hydroxycholesterol as a research-grade chemical. The exact purity is specified on the Certificate of Analysis provided with each batch. We do not represent this product as USP, BP, or EP grade.

What are the safety and handling precautions for 22(S)-Hydroxycholesterol?

Handle 22(S)-Hydroxycholesterol with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for detailed information. It has a WGK rating of 3 in Germany, indicating a high hazard to water.

How is 22(S)-Hydroxycholesterol packed, shipped, and exported?

Tech Serve Solutions professionally packs, ships, and exports 22(S)-Hydroxycholesterol globally, adhering to all relevant regulations for chemical transport.