2R, 4R-APDC monohydrate
2R,4R-APDC monohydrate (CAS 169209-63-6) is a white powder identified by the empirical formula C6H10N2O4 · H2O and a molecular weight of 192.17. As a Group II mGluR metabotropic glutamate receptor agonist, it is a key research tool in cell biology and neuroscience. This compound serves as a valuable reagent in studies of cell signalling pathways and as a potential therapeutic agent within drug discovery programs.
- IUPAC
- 4-amino-2,4-pyrrolidinedicarboxylic acid
- Synonyms
- 4-amino-2,4-pyrrolidinedicarboxylic acid monohydrate
Metabotropic Glutamate Receptor Agonist
2R,4R-APDC monohydrate functions as a selective agonist for Group II metabotropic glutamate receptors (mGluRs). It is used in research to investigate the physiological roles of mGluRs in the central nervous system, particularly in neuronal excitability and synaptic transmission.
Neuroscience Research Tool
This compound aids in understanding neurochemical processes and neurological disorders. Its application spans studies on neurotransmission, neuronal plasticity, and potential therapeutic interventions for conditions affecting the nervous system.
Cell Signalling Investigations
As a bioactive small molecule, 2R,4R-APDC monohydrate is employed to probe intracellular signalling cascades triggered by mGluR activation. This supports research in cellular communication and responses.
Drug Discovery and Development
The compound is recognised as an approved therapeutic candidate and is utilised in preclinical research for developing novel pharmaceuticals. Its agonist activity makes it a valuable lead compound for exploring treatments targeting mGluR pathways.
| Molecular weight | 192.17 |
|---|---|
| Empirical formula | C6H10N2O4 · H2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: ≥2 mg/mL |
| Storage temperature | room temp |
| Application | 2R,4R-APDC is a Group II mGluR metabotropic glutamate receptor agonist. |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2R,4R-APDC monohydrate used for?
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2R,4R-APDC monohydrate is used as a Group II mGluR metabotropic glutamate receptor agonist in neuroscience research, cell signalling studies, and drug discovery programs.
What are the CAS number and formula for 2R,4R-APDC monohydrate?
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The CAS number for 2R,4R-APDC monohydrate is 169209-63-6 (for the anhydrous form). The empirical formula is C6H10N2O4 · H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2R,4R-APDC monohydrate with an assay of ≥98% by HPLC. We do not represent this product as USP, BP, or EP grade.
How should 2R,4R-APDC monohydrate be handled?
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2R,4R-APDC monohydrate is a Warning substance, classified under GHS07. It may cause harm if swallowed (H302), skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding dust formation and contact with skin and eyes. Refer to the Safety Data Sheet for full details.
How is 2R,4R-APDC monohydrate shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. We ensure appropriate packaging and documentation for the safe and compliant shipment of 2R,4R-APDC monohydrate worldwide.
How can I request a quote or sample?
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To request a quote or sample of 2R,4R-APDC monohydrate, please contact our sales department through our website or by phone, providing your specific requirements.
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