Chlorotris(triethylsilyl)silane
Chlorotris(triethylsilyl)silane (CAS: 30432-47-4) is a silicon-based chemical compound with the molecular formula C18H45ClSi4 and a molecular weight of 409.34 g/mol. This reagent is primarily utilised in chemical synthesis, particularly as a protecting and derivatizing agent. Its unique structure makes it valuable for specific transformations in organic chemistry, offering controlled silylation.
- IUPAC
- Supersilyl TES
- Synonyms
- Supersilyl TES

Protecting Group Reagent
Chlorotris(triethylsilyl)silane is employed as a silylating agent to protect sensitive functional groups during complex organic syntheses. The resulting silyl ethers are stable under various reaction conditions but can be readily cleaved when needed.
Derivatization Agent
In analytical chemistry, this compound can be used to derivatize analytes, improving their volatility or detectability for techniques like gas chromatography. This facilitates the identification and quantification of specific chemical species.
Organic Synthesis
It serves as a versatile reagent in advanced organic synthesis pathways. Its application aids in the selective modification of molecules, contributing to the development of novel compounds and materials.
| Molecular weight | 409.34 |
|---|---|
| Empirical formula | C18H45ClSi4 |
| Density | 0.941 g/mL at 25 °C |
| Refractive index | n20/D 1.535 |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
| Supplemental hazards | Contact with water liberates toxic gas. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorotris(triethylsilyl)silane used for?
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Chlorotris(triethylsilyl)silane is used in chemical synthesis, predominantly as a protecting and derivatizing reagent. It is valuable for protecting functional groups and for derivatizing analytes in organic chemistry.
What are the CAS number and chemical formula for Chlorotris(triethylsilyl)silane?
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The CAS number for Chlorotris(triethylsilyl)silane is 30432-47-4, and its empirical formula in Hill notation is C18H45ClSi4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chlorotris(triethylsilyl)silane with a purity indicated by its refractive index (n20/D 1.535) and density (0.941 g/mL at 25 °C). This product is supplied for research and technical purposes and is not represented as USP, BP, or EP grade.
How should Chlorotris(triethylsilyl)silane be handled safely?
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Chlorotris(triethylsilyl)silane is a Warning substance (GHS07) with hazards H315, H319, and H335, causing skin, eye, and respiratory irritation. Importantly, it liberates toxic gas upon contact with water. Handle with adequate ventilation, wear protective gloves, eye protection, and ensure it does not contact moisture.
How is Chlorotris(triethylsilyl)silane packed, shipped, and exported?
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TSS exports Chlorotris(triethylsilyl)silane globally, adhering to all necessary regulations for the safe transport of chemicals. Packaging is designed to maintain product integrity and safety during transit. Please contact us for specific shipping details to your region.
How can I request a sample or a quote for Chlorotris(triethylsilyl)silane?
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To request a sample or a quote for Chlorotris(triethylsilyl)silane, please use the contact form on our website or reach out to our sales team directly via email or phone. Please provide your contact details and the quantity required.
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