Chlorotripropylsilane

CAS 995-25-5(CH3CH2CH2)3SiClChemical Synthesis

Chlorotripropylsilane (CAS: 995-25-5) is a silicon-based organic compound with the linear formula (CH3CH2CH2)3SiCl and a molecular weight of 192.80 g/mol. This chemical serves as a valuable reagent in organic synthesis, particularly in applications involving silicon chemistry. Its structure makes it useful for derivatization and protection strategies in complex molecular syntheses, contributing to the development of new materials and pharmaceuticals.

IUPAC: Tripropylchlorosilane

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Chlorotripropylsilane ((CH3CH2CH2)3SiCl) — chemical structure, CAS 995-25-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisSilicon-BasedSynthetic Reagents

01 /Applications

Protecting Group Chemistry

Chlorotripropylsilane can be employed to introduce tripropylsilyl (TPS) protecting groups onto hydroxyl or amine functionalities. This reversible protection strategy is crucial in multi-step organic syntheses where specific reactive sites need to be temporarily masked.

Derivatization Reagent

As a derivatizing agent, it can modify molecules to improve their analytical properties, such as volatility for gas chromatography, or to facilitate further chemical transformations. Its silicon backbone offers unique steric and electronic influences.

Organic Synthesis Intermediate

This compound acts as a versatile intermediate in the synthesis of more complex organosilicon compounds. It facilitates the formation of Si-C, Si-O, or Si-N bonds, essential for creating novel materials and functional molecules.

02 /Properties

Molecular weight	192.80
Linear formula	(CH3CH2CH2)3SiCl
Assay	98%
Boiling point	202 °C(lit.)
Density	0.882 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.44(lit.)

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Danger

Hazard statements

H314Causes severe skin burns and eye damage
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	63 °C / 145.4 °F
Transport (UN / ADR)	UN 2987 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	14-35-37
Safety statements (S)	26-36/37/39-45
Supplemental hazards	Reacts violently with water.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

995-25-5

MDL number

MFCD00000508

PubChem substance

24855384

Beilstein registry

1737489

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Chlorotripropylsilane used for?

Chlorotripropylsilane is primarily used as a reagent in organic synthesis for protection and derivatization strategies, especially in the creation of complex organosilicon compounds.

What is the CAS number and formula for Chlorotripropylsilane?

The CAS number is 995-25-5 and the linear formula is (CH3CH2CH2)3SiCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Chlorotripropylsilane with an assay of 98%. We do not represent this product as USP, BP, or EP grade.

How should Chlorotripropylsilane be handled safely?

Chlorotripropylsilane is a corrosive liquid that reacts violently with water. Handle with extreme care, wearing appropriate personal protective equipment including faceshields, goggles, gloves, and a suitable respirator. Ensure adequate ventilation.

Is Chlorotripropylsilane packed, shipped, or exported by TSS?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Chlorotripropylsilane, adhering to all relevant shipping regulations.