Chlorotris(trimethylsilyl)silane
Chlorotris(trimethylsilyl)silane (CAS 5565-32-2) is a silicon-based organosilicon compound with a molecular weight of 283.11 g/mol. Its structure features a silicon atom bonded to three trimethylsilyl groups and one chlorine atom. This compound serves as a versatile reagent in organic synthesis, particularly in the formation of silyl ethers and as a precursor in advanced silicon-based material research and protection chemistry.
![Chlorotris(trimethylsilyl)silane ([(CH3)3Si]3SiCl) — chemical structure, CAS 5565-32-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F5565-32-2.png&w=3840&q=75)
Super Silyl Protecting Groups
Chlorotris(trimethylsilyl)silane is employed in the creation of 'Super Silyl' protecting groups, offering robust protection strategies in complex organic syntheses.
Phosphorus Chemistry
This reagent is utilised for insertion reactions into P-P bonds, enabling the preparation of novel silyl-substituted phosphines and diphosphines.
Stereoselective Synthesis
It participates in diastereoselective aldol and cascade reactions, contributing to the stereocontrolled formation of carbon-carbon bonds.
| Molecular weight | 283.11 |
|---|---|
| Linear formula | [(CH3)3Si]3SiCl |
| Assay | 97% |
| Density | 0.877 g/mL at 25 °C |
| Concentration | 50 wt. % in toluene |
| Application | Super Silyl Protecting GroupsUsed for:• Insertion into a P-P bond1• Diastereoselective aldol and cascade reactions2• Preparation of hypersilyl substituted monophosphines and diphosphines3 |
| Melting point | 50-52 °C(lit.) |
Hazard statements
- H228Flammable solid
- H261In contact with water releases flammable gas
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P422
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 31 °C / 87.8 °F |
| Transport (UN / ADR) | UN 3132 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-29-36/37/38 |
| Safety statements (S) | 7/8-16-26-36/37-43-Neverusewater. |
| Supplemental hazards | Contact with water liberates toxic gas. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorotris(trimethylsilyl)silane used for?
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Chlorotris(trimethylsilyl)silane is used in organic synthesis, particularly for the formation of silyl protecting groups, insertion into P-P bonds, and in diastereoselective aldol and cascade reactions.
What are the CAS number and chemical formula for Chlorotris(trimethylsilyl)silane?
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The CAS number is 5565-32-2, and the linear formula is [(CH3)3Si]3SiCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chlorotris(trimethylsilyl)silane with an assay of 97%. This is a technical/research grade product, and we do not represent it as USP, BP, EP, or any pharmacopoeia standard.
How should Chlorotris(trimethylsilyl)silane be handled safely?
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Chlorotris(trimethylsilyl)silane is flammable and reacts with water to release toxic gas. Handle with appropriate personal protective equipment, including eyeshields and gloves, in a well-ventilated area away from ignition sources and moisture. Refer to the Safety Data Sheet for full details.
How is Chlorotris(trimethylsilyl)silane packed and exported?
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Chlorotris(trimethylsilyl)silane is shipped under UN 3132, Packing Group III, requiring specific handling and packaging protocols for safe transport, both domestically and internationally.
How can I request a sample or quote for Chlorotris(trimethylsilyl)silane?
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To request a sample or a quote, please contact our sales department via the website or by phone, providing your contact details and the quantity required.
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