Chlorotriphenylsilane
Chlorotriphenylsilane (CAS 76-86-8) is a silicon-based organosilicon compound with the linear formula (C₆H₅)₃SiCl and a molecular weight of 294.85 g/mol. This white crystalline solid is primarily recognised for its utility in chemical synthesis. It serves as a valuable reagent, particularly in organic chemistry, where its reactivity is exploited for specific synthetic transformations and as a protecting group precursor.
- IUPAC
- TPSCl,Triphenylchlorosilane
- Synonyms
- TriphenylchlorosilaneTriphenylsilyl chlorideTPSCl

Protecting Group Chemistry
Chlorotriphenylsilane is used to introduce the triphenylsilyl (TPS) protecting group onto alcohols and other functional groups. This group offers stability under various reaction conditions and can be selectively removed when needed.
Organic Synthesis Reagent
It functions as a versatile reagent in organic synthesis, enabling the preparation of various organosilicon compounds. Its reactivity allows for the formation of new carbon-silicon bonds.
Derivatization Agent
This compound can be employed as a derivatizing agent to modify the properties of molecules, aiding in their analysis or facilitating subsequent reactions.
| Molecular weight | 294.85 |
|---|---|
| Linear formula | (C6H5)3SiCl |
| Assay | ≥97.0% (GC) |
| Solubility | acetone: soluble0.1 g/mL, clear |
| Melting point | 91-94 °C(lit.) |


Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorotriphenylsilane used for?
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Chlorotriphenylsilane is primarily used in chemical synthesis as a protecting group reagent, particularly for introducing the triphenylsilyl (TPS) group, and as a versatile reagent for creating organosilicon compounds.
What is the CAS number and formula for Chlorotriphenylsilane?
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The CAS number for Chlorotriphenylsilane is 76-86-8 and its linear formula is (C₆H₅)₃SiCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chlorotriphenylsilane with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, or EP grade.
How should Chlorotriphenylsilane be handled safely?
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Chlorotriphenylsilane is classified as Danger, causing severe skin burns and eye damage (H314) and may cause respiratory irritation (H335). Handling requires appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for full details.
How is Chlorotriphenylsilane packed and shipped?
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Chlorotriphenylsilane is packed in compliance with UN 3261 (Class 8, PGII) regulations for safe transport. TSS exports this chemical globally, adhering to all relevant shipping and customs requirements.
How can I request a sample or quote for Chlorotriphenylsilane?
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To request a sample or a quotation for Chlorotriphenylsilane, please contact our sales team through the website or by phone, providing your specific requirements.
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