Chloro(methyl)diphenylsilane
Chloro(methyl)diphenylsilane (CAS: 144-79-6) is an organosilicon compound with the formula CH3Si(C6H5)2Cl and a molecular weight of 232.78 g/mol. This chemical serves as a valuable reagent in organic synthesis, particularly in the field of silicon-based chemistry. It is frequently employed for protection and derivatization strategies, enabling selective transformations in complex molecular architectures. Its specific reactivity profile makes it a useful tool for chemists.
- IUPAC
- Chloro-diphenyl-methylsilane,DPMSCl,Diphenylmethylchlorosilane,Methyldiphenylchlorosilane
- Synonyms
- ChlordiphenylmethylsilaneDiphenylmethylchlorosilaneMethyldiphenylchlorosilaneDPMSCl
Protecting Group Reagent
Chloro(methyl)diphenylsilane is utilised as a reagent for introducing the diphenylmethylsilyl (DPMS) protecting group onto hydroxyl functionalities. This protection strategy is useful in multi-step syntheses where temporary masking of reactive alcohol groups is required.
Derivatization Agent
In analytical chemistry, it can be employed as a derivatizing agent to enhance the volatility or detectability of certain analytes. This can facilitate their analysis by techniques such as gas chromatography (GC).
Organic Synthesis Intermediate
As a silicon-based building block, it finds application in the synthesis of more complex organosilicon compounds. Its chloro functionality allows for nucleophilic substitution reactions, enabling the formation of new silicon-carbon or silicon-heteroatom bonds.
| Molecular weight | 232.78 |
|---|---|
| Linear formula | CH3Si(C6H5)2Cl |
| Assay | 98% |
| Boiling point | 295 °C(lit.) |
| Density | 1.107 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.574(lit.) |
| Vapour pressure | 3 mmHg (125 °C) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2987 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloro(methyl)diphenylsilane used for?
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Chloro(methyl)diphenylsilane (CAS: 144-79-6) is primarily used in organic synthesis as a reagent for introducing the diphenylmethylsilyl protecting group onto hydroxyl functions and as an intermediate in the preparation of other organosilicon compounds.
What is the CAS number and chemical formula for Chloro(methyl)diphenylsilane?
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The CAS number is 144-79-6, and the chemical formula is CH3Si(C6H5)2Cl.
What grade and purity does Tech Serve Solutions supply for Chloro(methyl)diphenylsilane?
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Tech Serve Solutions supplies Chloro(methyl)diphenylsilane with a minimum assay of 98%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should Chloro(methyl)diphenylsilane be handled safely?
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Chloro(methyl)diphenylsilane is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, goggles, and face shields, should be worn. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing. Refer to the Safety Data Sheet for full handling instructions.
How is Chloro(methyl)diphenylsilane packaged and shipped?
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This product is shipped as a hazardous material (UN 2987, Class 8, PG II). Packaging adheres to strict international regulations for the transport of dangerous goods.
How can I request a sample or a quote for Chloro(methyl)diphenylsilane?
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To request a sample or obtain a quote, please use the contact form on our website or reach out to our sales team directly, referencing the product name and CAS number 144-79-6.
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