2-Amino-6-methoxybenzothiazole
2-Amino-6-methoxybenzothiazole (CAS: 1747-60-0), with the molecular formula C8H8N2OS and a molecular weight of 180.23 g/mol, is a key heterocyclic building block. This compound is primarily utilised in organic synthesis. It serves as an intermediate in the creation of various complex molecules, including Schiff bases, 4-thiazolidinones, and the precursor to firefly luciferin.

Synthesis of Schiff Bases and 4-Thiazolidinones
2-Amino-6-methoxybenzothiazole is employed as a fundamental building block in the synthesis of novel series of Schiff bases and 4-thiazolidinones. These derivatives can be explored for various chemical research applications.
Intermediate for Firefly Luciferin Synthesis
This compound is a crucial intermediate in the preparation of 2-cyano-6-methoxybenzothiazole. This derivative is essential for the synthesis pathway leading to firefly luciferin, a bioluminescent compound.
General Organic Synthesis
As a versatile heterocyclic building block, 2-Amino-6-methoxybenzothiazole finds application in broader organic synthesis projects requiring the benzothiazole scaffold.
| Molecular weight | 180.23 |
|---|---|
| Empirical formula | C8H8N2OS |
| Assay | 98% |
| Application | 2-Amino-6-methoxybenzothiazole was used as building block in the syntheses of novel series of Schiff bases and 4-thiazolidinones1. It was used in the synthesis of 2-cyano-6-methoxybenzothiazole, key intermediate for the synthesis of firefly luciferin2. |
| Melting point | 165-167 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-6-methoxybenzothiazole used for?
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2-Amino-6-methoxybenzothiazole is used as a building block in organic synthesis, notably for preparing Schiff bases, 4-thiazolidinones, and as a key intermediate in the synthesis of firefly luciferin.
What are the CAS number and chemical formula for 2-Amino-6-methoxybenzothiazole?
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The CAS number for 2-Amino-6-methoxybenzothiazole is 1747-60-0, and its chemical formula is C8H8N2OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-6-methoxybenzothiazole with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2-Amino-6-methoxybenzothiazole be handled safely?
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Handle with appropriate personal protective equipment including a dust mask (N95 or equivalent), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. This compound is classified as harmful if swallowed and causes skin, eye, and respiratory irritation (H302, H315, H319, H335).
How is 2-Amino-6-methoxybenzothiazole packed and shipped?
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Products are carefully packed and exported by Tech Serve Solutions in compliance with international shipping regulations for chemical compounds.
How can I request a sample or quote for 2-Amino-6-methoxybenzothiazole?
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Please contact our sales team via the website or direct email to request a sample or a quotation for 2-Amino-6-methoxybenzothiazole.
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