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Chloro(dimethyl)phenylsilane

CAS 768-33-2C6H5Si(CH3)2ClChemical Synthesis

Chloro(dimethyl)phenylsilane (CAS: 768-33-2, Formula: C6H5Si(CH3)2Cl, MW: 170.71) is a reactive organosilicon compound. It serves as a valuable intermediate and reagent in chemical synthesis, particularly in the introduction of the dimethylphenylsilyl protecting group. Its utility extends to laboratory research and the development of novel materials and pharmaceuticals.

IUPAC
DMPSCl,Dimethylphenylchlorosilane,Dimethylphenylsilylchloride,Phenyldimethylchlorosilane
Synonyms
DMPSClDimethylphenylchlorosilaneDimethylphenylsilylchloridePhenyldimethylchlorosilane
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Chloro(dimethyl)phenylsilane (C6H5Si(CH3)2Cl) — chemical structure, CAS 768-33-2; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical SynthesisSilicon-BasedSynthetic Reagents
01 /Applications

Protecting Group Chemistry

Utilised for the temporary protection of hydroxyl and amine functionalities in organic synthesis. The dimethylphenylsilyl group offers distinct cleavage conditions compared to other silyl protecting groups.

Organosilicon Synthesis

Acts as a precursor in the synthesis of more complex organosilicon compounds and polymers. It facilitates the formation of silicon-carbon bonds.

Derivatization Reagent

Employed in analytical chemistry for derivatizing compounds to improve their chromatographic properties or detectability.

02 /Properties
Molecular weight170.71
Linear formulaC6H5Si(CH3)2Cl
Assay98%
Density1.017 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.509(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point62 °C / 143.6 °F
Transport (UN / ADR)UN 2987 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34-37
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
768-33-2
MDL number
MFCD00000499
PubChem substance
24887297
Beilstein registry
606292
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Chloro(dimethyl)phenylsilane used for?

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Chloro(dimethyl)phenylsilane is primarily used as a reagent in chemical synthesis for introducing the dimethylphenylsilyl protecting group onto hydroxyl and amine functionalities, and as a building block for organosilicon compounds.

What are the CAS number and formula for Chloro(dimethyl)phenylsilane?

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The CAS number is 768-33-2 and the molecular formula is C6H5Si(CH3)2Cl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Chloro(dimethyl)phenylsilane with a minimum assay of 98%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.

How should Chloro(dimethyl)phenylsilane be handled safely?

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Chloro(dimethyl)phenylsilane is classified as Danger, causing severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment including full-face shields, chemical-resistant gloves, and goggles. Ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling instructions.

How is Chloro(dimethyl)phenylsilane packaged and shipped?

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Chloro(dimethyl)phenylsilane is shipped as a hazardous material (UN 2987, Class 8, Packing Group II). Packaging complies with international transport regulations for corrosive substances.

How can I request a sample or quote for Chloro(dimethyl)phenylsilane?

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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through our website or by email, providing your specific requirements.

Need Chloro(dimethyl)phenylsilane in a specific grade or volume?