Chloro(dimethyl)isopropylsilane
Chloro(dimethyl)isopropylsilane (CAS 3634-56-8) is a silicon-based organic compound with the linear formula (CH3)2CHSi(CH3)2Cl and a molecular weight of 136.70 g/mol. This flammable and corrosive liquid serves as a valuable reagent in chemical synthesis, particularly for protection and derivatization strategies in organic chemistry. Its specific reactivity makes it useful in various laboratory and industrial applications.
- IUPAC
- Chloro-isopropyl-dimethylsilane,DMIPSCl,Dimethylisopropylchlorosilane,Dimethylisopropylsilyl chloride,Isopropyldimethylchlorosilane
- Synonyms
- DimethylisopropylchlorosilaneIsopropyldimethylchlorosilaneChloro-isopropyl-dimethylsilaneDMIPSClDimethylisopropylsilyl chloride
Protecting Group Reagent
Chloro(dimethyl)isopropylsilane is employed in organic synthesis to introduce the dimethylisopropylsilyl (DMIPS) protecting group onto hydroxyl functionalities. This protection strategy is crucial for multi-step syntheses where sensitive alcohol groups need to be temporarily masked.
Derivatization Agent
This silane can be used as a derivatizing agent in analytical chemistry. By reacting with specific functional groups, it can alter the compound's properties, such as volatility or detectability, aiding in chromatographic analysis (e.g., GC-MS).
Intermediate in Organosilicon Chemistry
As a functionalized organosilicon compound, it serves as a building block for synthesizing more complex silicon-containing molecules, polymers, or materials with tailored properties.
| Molecular weight | 136.70 |
|---|---|
| Linear formula | (CH3)2CHSi(CH3)2Cl |
| Assay | 97% |
| Boiling point | 109-110 °C/738 mmHg(lit.) |
| Density | 0.869 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.416(lit.) |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 15 °C / 59 °F |
| Transport (UN / ADR) | UN 2985 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34-37 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloro(dimethyl)isopropylsilane used for?
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Chloro(dimethyl)isopropylsilane is primarily used as a protecting group reagent for alcohols in organic synthesis and as a derivatizing agent in analytical chemistry. It also functions as an intermediate in the synthesis of various organosilicon compounds.
What is the CAS number and formula for Chloro(dimethyl)isopropylsilane?
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The CAS number for Chloro(dimethyl)isopropylsilane is 3634-56-8, and its linear formula is (CH3)2CHSi(CH3)2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chloro(dimethyl)isopropylsilane with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Chloro(dimethyl)isopropylsilane be handled safely?
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Chloro(dimethyl)isopropylsilane is a highly flammable liquid and causes severe skin burns and eye damage. Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment including chemical-resistant gloves, eye protection (goggles and face shield), and respiratory protection. Keep away from heat, sparks, and open flames. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
Is Chloro(dimethyl)isopropylsilane a controlled substance?
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The provided data does not indicate that Chloro(dimethyl)isopropylsilane is a controlled substance.
How is Chloro(dimethyl)isopropylsilane packed, shipped, and exported?
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As a specialist global supplier and exporter, Tech Serve Solutions ensures that Chloro(dimethyl)isopropylsilane is packaged, shipped, and exported in compliance with all relevant international regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a sample or quote for Chloro(dimethyl)isopropylsilane?
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To request a sample or a quote for Chloro(dimethyl)isopropylsilane, please contact our sales department via the website or by phone, providing your specific requirements.
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