Chloro(dimethyl)octadecylsilane
Chloro(dimethyl)octadecylsilane (CAS: 18643-08-8) is a silicon-based organic compound with the formula CH3(CH2)17Si(CH3)2Cl and a molecular weight of 347.09 g/mol. This silylating reagent is primarily utilised in chemical synthesis for the protection and derivatisation of molecules, particularly in organic chemistry and analytical applications. Its long alkyl chain influences its solubility and reactivity in various organic media.
- IUPAC
- Dimethyloctadecylchlorosilane,Octadecyldimethylchlorosilane
Silylating Reagent in Organic Synthesis
Chloro(dimethyl)octadecylsilane serves as a versatile silylating agent. It is employed to introduce the dimethyl-octadecylsilyl group onto various functional groups, such as hydroxyl or amine groups, thereby protecting them during multi-step syntheses.
Derivatisation for Analytical Chemistry
The reagent can be used for derivatisation to enhance the volatility or detectability of certain analytes in techniques like gas chromatography (GC) or mass spectrometry (MS). The long octadecyl chain can also impart unique chromatographic properties.
Surface Modification
Silicon-based compounds like this can be used to modify the surface properties of materials. Chloro(dimethyl)octadecylsilane may be applied to introduce hydrophobic characteristics or to functionalise surfaces for specific binding or interaction studies.
| Molecular weight | 347.09 |
|---|---|
| Linear formula | CH3(CH2)17Si(CH3)2Cl |
| Assay | 95% |
| Boiling point | 145-155 °C/0.005 mmHg(lit.) |
| Density | 0.86 g/mL at 20 °C(lit.) |
| Concentration | 70% in toluene |
| Application | Silylating reagent |
| Melting point | 28-30 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 200 °C / 392 °F |
| Transport (UN / ADR) | UN 2987 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloro(dimethyl)octadecylsilane used for?
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Chloro(dimethyl)octadecylsilane is primarily used as a silylating reagent in chemical synthesis for the protection and derivatisation of molecules, and in analytical chemistry for modifying analyte properties.
What is the CAS number and chemical formula for Chloro(dimethyl)octadecylsilane?
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The CAS number is 18643-08-8 and the chemical formula is CH3(CH2)17Si(CH3)2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chloro(dimethyl)octadecylsilane with an assay of 95%. We do not represent this product as USP, EP, or any pharmacopoeia grade; it is suitable for research and general synthetic applications.
How should Chloro(dimethyl)octadecylsilane be handled safely?
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This compound is corrosive and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment including gloves, eye shields, and face shields. Ensure adequate ventilation. Refer to the safety data sheet for full handling procedures.
Is Chloro(dimethyl)octadecylsilane a controlled substance?
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Based on the provided data, there is no indication that Chloro(dimethyl)octadecylsilane is a controlled or scheduled substance.
How is Chloro(dimethyl)octadecylsilane packed and shipped?
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Products are typically packed according to industry standards for safe transport. For international export, adherence to specific regulations, including UN 2987 8 / PGII classification, is maintained.
How can I request a quote or sample of Chloro(dimethyl)octadecylsilane?
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To request a quote or a sample, please use the contact form on our website or reach out to our sales department directly, providing the product name and CAS number.
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