Chloro(dimethyl)thexylsilane
Chloro(dimethyl)thexylsilane (CAS 67373-56-2) is a silicon-based chemical compound with the linear formula (CH3)2CHC(CH3)2Si(CH3)2Cl and a molecular weight of 178.77 g/mol. It is primarily utilised as a reagent in chemical synthesis, particularly in the protection and derivatization of functional groups. Its specific structure makes it valuable in organic chemistry for introducing the thexyldimethylsilyl group.
- IUPAC
- Chlorodimethyl(1,1,2-trimethylpropyl)silane,Dimethyl-(2,3-dimethyl-2-butyl)chlorosilane,Dimethyl-thexylchlorosilane,Dimethylthexylsilyl chloride,TDSCl,Thexyldimethylsilyl chloride
- Synonyms
- Chlorodimethyl(1,1,2-trimethylpropyl)silaneDimethyl-(2,3-dimethyl-2-butyl)chlorosilaneDimethyl-thexylchlorosilaneDimethylthexylsilyl chlorideTDSClThexyldimethylsilyl chloride
Protecting Group Reagent
Chloro(dimethyl)thexylsilane is employed to introduce the thexyldimethylsilyl (TDS) protecting group onto hydroxyl, amine, or other nucleophilic functionalities. This protection strategy is useful in multi-step organic syntheses where certain functional groups need to be temporarily masked.
Derivatization Agent
In analytical chemistry, this compound can be used for derivatization to enhance the volatility or detectability of certain analytes, particularly in gas chromatography (GC). The resulting silyl derivatives often exhibit improved chromatographic properties.
Synthetic Intermediate
As a functionalised organosilicon compound, it serves as a building block in the synthesis of more complex silicon-containing molecules and materials. Its reactivity allows for further chemical transformations.
| Molecular weight | 178.77 |
|---|---|
| Linear formula | (CH3)2CHC(CH3)2Si(CH3)2Cl |
| Assay | ≥97.0% (GC) |
| Boiling point | 55-56 °C/10 mmHg(lit.) |
| Density | 0.909 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.449(lit.)n20/D 1.450 |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 46 °C / 114.8 °F |
| Transport (UN / ADR) | UN 2986 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloro(dimethyl)thexylsilane used for?
+
Chloro(dimethyl)thexylsilane is primarily used as a protecting group reagent in organic synthesis and as a derivatization agent, particularly for analytical purposes like gas chromatography.
What is the CAS number and chemical formula for Chloro(dimethyl)thexylsilane?
+
The CAS number is 67373-56-2 and the linear formula is (CH3)2CHC(CH3)2Si(CH3)2Cl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Chloro(dimethyl)thexylsilane with an assay of ≥97.0% (GC). We do not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards.
How should Chloro(dimethyl)thexylsilane be handled?
+
This compound is flammable and corrosive. Handle with appropriate personal protective equipment including gloves, eye protection (goggles and face shield), and respiratory protection. Ensure adequate ventilation and avoid contact with skin, eyes, and clothing. Store away from heat and ignition sources.
Is Chloro(dimethyl)thexylsilane a controlled substance?
+
No, there is no indication in the provided data that Chloro(dimethyl)thexylsilane is a controlled or scheduled substance.
How is Chloro(dimethyl)thexylsilane packed, shipped, and exported?
+
As a specialist supplier and exporter, Tech Serve Solutions ensures that Chloro(dimethyl)thexylsilane is packed, shipped, and exported in compliance with all relevant international regulations for hazardous materials, such as UN 2986, Class 3(8), Packing Group II.
How can I request a sample or a quote for Chloro(dimethyl)thexylsilane?
+
To request a sample or obtain a quotation for Chloro(dimethyl)thexylsilane, please contact our sales department through the TSS website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis