Chloro(methyl)phenylsilane
Chloro(methyl)phenylsilane (CAS: 1631-82-9, C6H5SiH(CH3)Cl) is a silicon-based organic compound with a molecular weight of 156.68 g/mol. This reagent is primarily utilised in chemical synthesis, particularly as a protecting or derivatizing agent in organic chemistry. Its reactive nature makes it valuable for introducing specific functional groups in complex molecular structures and for analytical purposes.
- IUPAC
- Methyl-phenyl-chlorosilane
- Synonyms
- Methyl-phenyl-chlorosilane

Protecting Group Chemistry
Chloro(methyl)phenylsilane can be employed to introduce the methylphenylsilyl group, acting as a protecting group for alcohols and other functional groups during multi-step syntheses. This protection strategy is crucial for selectively reacting other parts of a molecule.
Derivatization Reagent
In analytical chemistry, it serves as a derivatizing agent to improve the detectability or separability of analytes, often by gas chromatography. The silylation of active hydrogens can enhance volatility and thermal stability.
Organic Synthesis Intermediate
This silane acts as a versatile building block in organic synthesis, enabling the formation of carbon-silicon bonds and the construction of organosilicon compounds with diverse applications.
| Molecular weight | 156.68 |
|---|---|
| Linear formula | C6H5SiH(CH3)Cl |
| Assay | ≥93.0% (GC) |
| Boiling point | 113 °C(lit.) |
| Density | 1.043 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.515(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 62 °C / 143.6 °F |
| Transport (UN / ADR) | UN 2987 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 26-36/37/39-43-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloro(methyl)phenylsilane used for?
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Chloro(methyl)phenylsilane is primarily used in chemical synthesis, often as a protecting or derivatizing reagent for organic molecules, and as a building block for organosilicon compounds.
What is the CAS number and formula for Chloro(methyl)phenylsilane?
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The CAS number is 1631-82-9, and the chemical formula is C6H5SiH(CH3)Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chloro(methyl)phenylsilane with a purity of ≥93.0% (GC). TSS does not represent this product as USP, BP, EP or other pharmacopoeia grades.
How should Chloro(methyl)phenylsilane be handled safely?
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Chloro(methyl)phenylsilane is a corrosive substance that reacts violently with water. Handling requires appropriate personal protective equipment including a full-face respirator, gloves, and goggles, and should be done in a well-ventilated area away from moisture. Always consult the Safety Data Sheet (SDS) before use.
How is Chloro(methyl)phenylsilane packed and exported?
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Chloro(methyl)phenylsilane is classified as UN 2987, Class 8, Packing Group II. It is shipped and exported in compliance with international regulations for hazardous materials.
How can I request a quote or sample of Chloro(methyl)phenylsilane?
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To request a quote or sample of Chloro(methyl)phenylsilane, please contact our sales team through the website or by phone, providing your specific requirements.
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