Chloro-dimethyl(3,3,3-trifluoropropyl)silane
Chloro-dimethyl(3,3,3-trifluoropropyl)silane (CAS: 1481-41-0) is a silicon-based compound with a molecular weight of 190.67 g/mol. This organosilicon halide is primarily utilised as a versatile reagent in chemical synthesis, particularly in organic chemistry. Its unique trifluoropropyl group offers specific reactivity and properties, making it valuable for introducing this moiety into various molecular structures. It is employed in protection and derivatization strategies.
- IUPAC
- Dimethyl(3,3,3-trifluoropropyl)chlorosilane
- Synonyms
- 1481-41-0C5H10ClF3SiDimethyl(3,3,3-trifluoropropyl)chlorosilane

Chemical Synthesis Reagent
Utilised as a building block or reagent in the synthesis of complex organic molecules. Its trifluoropropyl group can be incorporated into target structures to modify their properties.
Protecting Group Chemistry
Can serve as a reagent for the protection of functional groups during multi-step synthesis. The silane moiety offers selective protection and deprotection strategies.
Derivatization Agent
Employed for the derivatization of compounds, often to enhance their detectability or separability in analytical techniques like chromatography.
Organosilicon Chemistry
A key intermediate in the synthesis of specialised silicon-containing compounds, contributing to the field of materials science and advanced organic chemistry.
| Molecular weight | 190.67 |
|---|---|
| Empirical formula | C5H10ClF3Si |
| Assay | ≥95.0% (GC) |
| Boiling point | 118 °C(lit.) |
| Density | 1.117 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.378(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 20 °C / 68 °F |
| Transport (UN / ADR) | UN 2985 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloro-dimethyl(3,3,3-trifluoropropyl)silane used for?
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Chloro-dimethyl(3,3,3-trifluoropropyl)silane is used as a reagent in chemical synthesis, particularly for protection and derivatization strategies, and in organosilicon chemistry.
What is the CAS number and formula for Chloro-dimethyl(3,3,3-trifluoropropyl)silane?
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The CAS number is 1481-41-0 and the empirical formula (Hill notation) is C5H10ClF3Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chloro-dimethyl(3,3,3-trifluoropropyl)silane with an assay of ≥95.0% (GC). We do not represent this product as USP, BP, or EP grade.
How should Chloro-dimethyl(3,3,3-trifluoropropyl)silane be handled safely?
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This compound is flammable and causes severe skin burns and eye damage (Danger: H225, H314). Handle with extreme care, using appropriate personal protective equipment including a full-face respirator, chemical-resistant gloves, and eye protection, in a well-ventilated area. Refer to the Safety Data Sheet for full handling instructions.
Is Chloro-dimethyl(3,3,3-trifluoropropyl)silane regulated or scheduled?
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The provided data does not indicate that Chloro-dimethyl(3,3,3-trifluoropropyl)silane is a controlled or scheduled substance.
How is Chloro-dimethyl(3,3,3-trifluoropropyl)silane packed and shipped?
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This chemical is shipped as UN 2985, Class 8 (3), Packing Group II, indicating it is a corrosive liquid, flammable, in limited quantities. TSS exports globally following all relevant transport regulations.
How can I request a quote or sample?
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To request a quote or sample of Chloro-dimethyl(3,3,3-trifluoropropyl)silane, please contact our sales department through the TSS website or by phone, providing your specific requirements.
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