Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate
Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate (CAS: 207915-99-9) is a chemical synthesis reagent with a molecular weight of 280.58 g/mol. It is primarily used in the synthesis of onium salts for peptide coupling reactions and as a safer alternative to other coupling reagents. This compound also finds application in the synthesis of cytotoxic agents and bioconjugation reagents, serving as a versatile tool in organic and medicinal chemistry.
- IUPAC
- TCFH
- Synonyms
- N′-tetramethylformamidinium hexafluorophosphateC5H12ClF6N2P
Peptide Synthesis Reagent
Serves as a reactant in the synthesis of onium salts crucial for efficient peptide coupling reactions. It offers a modern approach to peptide bond formation in organic synthesis.
Synthesis of Safer Coupling Agents
This compound is employed in the development of alternative coupling reagents designed to be safer than traditional options. This contributes to improved laboratory safety and process efficiency.
Cytotoxin and Bioconjugation Synthesis
Used as a reagent in the synthesis of cancer cell cytotoxins and bioconjugation reagents. These applications highlight its utility in medicinal chemistry and biochemical research.
| Molecular weight | 280.58 |
|---|---|
| Empirical formula | C5H12ClF6N2P |
| Assay | ≥98.0% (T) |
| Storage temperature | 2-8°C |
| Application | Reactant for: Synthesis of onium salts for use in peptide coupling1 Synthesis of safer replacement for coupling reagents2Reagent for: Synthesis of cancer cell cytotoxins3 Synthesis of bioconjugation reagent4 |
| Melting point | 100-106 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate used for?
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Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate is used as a reactant in the synthesis of onium salts for peptide coupling and as a safer replacement for certain coupling reagents. It is also utilized in the synthesis of cancer cell cytotoxins and bioconjugation reagents.
What is the CAS number and chemical formula for this compound?
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The CAS number is 207915-99-9 and the empirical formula (Hill notation) is C5H12ClF6N2P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥98.0% (T). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate be handled?
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This compound is a Warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use with adequate ventilation, wear suitable personal protective equipment including eyeshields, gloves, and a dust mask (N95 type). Avoid breathing dust.
How is this chemical packed, shipped, and exported?
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The compound is stored at 2-8°C. TSS is a specialist global supplier and exporter of fine chemicals, offering reliable shipping and export services worldwide.
How can I request a sample or quote for this product?
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Please contact the TSS sales team directly through our website or by phone to request a sample or obtain a quotation for Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate.
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