Calcineurin autoinhibitory fragment
Calcineurin autoinhibitory fragment (CAS: 148067-21-4), with the molecular formula C124H205N39O39S2, is a peptide comprising 25 amino acids. This compound functions as a membrane-impermeable blocker of calcineurin, a key enzyme in cellular signalling pathways. It is primarily utilised in biochemical research for studying enzyme inhibition and cellular processes, particularly within cell biology and neuroscience research contexts.
- IUPAC
- Ile-Thr-Ser-Phe-Glu-Glu-Ala-Lys-Gly-Leu-Asp-Arg-Ile-Asn-Glu-Arg-Met-Pro-Pro-Arg-Arg-Asp-Ala-Met-Pro
Calcineurin Inhibition Studies
This peptide acts as a specific, membrane-impermeable inhibitor of calcineurin. It is valuable for researchers investigating the role of calcineurin in various cellular processes, including T-cell activation and immune responses.
Cellular Signalling Research
Utilised in cell biology and neuroscience research, the autoinhibitory fragment helps delineate the calcineurin-dependent signalling cascades. Its use allows for precise modulation of calcineurin activity in experimental settings.
Biochemical Assays
The compound serves as a tool in biochemical assays designed to study enzyme kinetics and substrate interactions related to calcineurin. Its defined sequence and purity make it suitable for quantitative analyses.
| Molecular weight | 2930.32 |
|---|---|
| Empirical formula | C124H205N39O39S2 |
| Assay | ≥90% (HPLC) |
| Storage temperature | −20°C |
| Application | Membrane-impermeable blocker of calcineurin.1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Calcineurin autoinhibitory fragment used for?
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Calcineurin autoinhibitory fragment (CAS: 148067-21-4) is used as a membrane-impermeable blocker of calcineurin in biochemical and cell biology research. It is particularly relevant for studies involving cell signalling, neuroscience, and enzyme inhibition.
What are the CAS number and molecular formula for Calcineurin autoinhibitory fragment?
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The CAS number for Calcineurin autoinhibitory fragment is 148067-21-4, and its molecular formula is C124H205N39O39S2.
What grade and purity does Tech Serve Solutions supply for Calcineurin autoinhibitory fragment?
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Tech Serve Solutions supplies Calcineurin autoinhibitory fragment with an assay of ≥90% by HPLC. This product is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety considerations when handling Calcineurin autoinhibitory fragment?
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When handling Calcineurin autoinhibitory fragment, it is essential to use personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The compound has a WGK Germany rating of 3, indicating a high level of hazard.
How is Calcineurin autoinhibitory fragment shipped and exported by TSS?
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Calcineurin autoinhibitory fragment is stored at -20°C. Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and documentation for international shipment of fine chemicals.
How can I request a sample or quote for Calcineurin autoinhibitory fragment?
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To request a sample or a quote for Calcineurin autoinhibitory fragment, please contact the Tech Serve Solutions sales team through our website or by phone. Our experts will assist you with your inquiry.
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