Calcium Ionophore A23187
Calcium Ionophore A23187 (CAS: 52665-69-7, C29H37N3O6) is a premium quality white to light yellow powder with a molecular weight of 523.62. This ionophore is highly selective for Ca2+ and plays a crucial role in cellular signalling research. It is known to potentiate responses to NMDA and stimulate nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase in cell culture.
- IUPAC
- Antibiotic A 23187,Calimycin
Calcium Ion Transport
Calcium Ionophore A23187 is a highly selective ionophore for Ca2+, facilitating its transport across biological membranes. This property makes it invaluable for studying intracellular calcium dynamics and signalling pathways.
Cellular Signalling Studies
This compound is widely used to investigate calcium-dependent cellular processes. It can potentiate responses to certain neurotransmitters and stimulate nitric oxide production, aiding research in neuroscience and cell biology.
Antibiotic Research
Recognised for its antibiotic properties, Calcium Ionophore A23187 is employed in research related to antibacterial mechanisms and the development of new antimicrobial agents.
| Molecular weight | 523.62 |
|---|---|
| Empirical formula | C29H37N3O6 |
| Assay | ≥98% (TLC) |
| Form | powder |
| Colour | white to light yellow |
| Solubility | ethanol: soluble5 mg/mL (with heating. Solutions are stable for at least 3 months at -20 °C when protected from light and water contamination.)DMSO: soluble50 mg/mL (with heating or sonication. Solutions are stable for at least 3 months at -20 °C when protected from light and water contamination.) |
| Storage temperature | 2-8°C |
| Application | Ionophore highly selective for Ca2+. Potentiates responses to NMDA but not quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Calcium Ionophore A23187 used for?
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Calcium Ionophore A23187 is used as a research tool to study calcium ion transport across membranes, cellular signalling pathways, and as an antibiotic in laboratory settings. It can potentiate NMDA responses and stimulate nitric oxide production.
What is the CAS number and chemical formula for Calcium Ionophore A23187?
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The CAS number is 52665-69-7, and the empirical formula is C29H37N3O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Calcium Ionophore A23187 at a PREMIUM quality level with an assay of ≥98% by TLC. This product is intended for laboratory and research use and is not supplied as USP, BP, or EP grade.
What are the safety considerations for handling Calcium Ionophore A23187?
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Calcium Ionophore A23187 is a potential irritant to the skin, eyes, and respiratory tract (H315, H319, H335). When handling, use a P261 respirator, wear eyeshields and gloves, and P305 + P351 + P338 when in eyes.
How is Calcium Ionophore A23187 packed and shipped?
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This product is typically supplied as a white to light yellow powder and is stored at 2-8°C. Tech Serve Solutions exports fine chemicals globally, adhering to all necessary regulations for safe and secure transport.
How can I request a quote or sample for Calcium Ionophore A23187?
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To request a quote or sample, please contact our sales department via our website or by phone, providing your contact details and the product name and CAS number.
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