Boc-Trp-OH

CAS 13139-14-5C16H20N2O4Chemical Synthesis

Nα-(tert-Butoxycarbonyl)-L-tryptophan, also known as Boc-Trp-OH (CAS: 13139-14-5), is a protected amino acid derivative with the chemical formula C16H20N2O4 and a molecular weight of 304.34 g/mol. It is primarily utilised as a building block in peptide synthesis and in chemical biology research. This compound is essential for creating complex peptide sequences where the tryptophan residue needs to be selectively protected.

IUPAC: Nα-(tert-Butoxycarbonyl)-L-tryptophan,Nα-Boc-L-tryptophan
Synonyms: Nα-(tert-Butoxycarbonyl)-L-tryptophanNα-Boc-L-tryptophan

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Boc-Trp-OH (C16H20N2O4) — chemical structure, CAS 13139-14-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisPeptide ChemistryTryptophan

01 /Applications

Peptide Synthesis

Boc-Trp-OH is a crucial protected amino acid derivative used in solid-phase and solution-phase peptide synthesis. The tert-butoxycarbonyl (Boc) protecting group allows for controlled coupling of the tryptophan residue into peptide chains.

Chemical Biology Research

In chemical biology, this compound serves as a versatile reagent for constructing modified peptides and peptidomimetics. Its inclusion can aid in studying protein-protein interactions or developing new therapeutic agents.

Organic Synthesis

Beyond peptide chemistry, Boc-Trp-OH finds application as an intermediate in general organic synthesis, particularly where a protected tryptophan moiety is required for further chemical transformations.

02 /Properties

Molecular weight	304.34
Empirical formula	C16H20N2O4
Assay	≥99.0% (TLC)
Optical activity	[α]20/D −20±1°, c = 1% in DMF
Melting point	136 °C (dec.)(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

13139-14-5

MDL number

MFCD00065595

Beilstein registry

39677

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-Trp-OH used for?

Boc-Trp-OH (Nα-(tert-Butoxycarbonyl)-L-tryptophan) is primarily used as a protected building block in peptide synthesis and in chemical biology research for creating complex peptide structures and modified peptides.

What are the CAS number and formula for Boc-Trp-OH?

The CAS number for Boc-Trp-OH is 13139-14-5, and its chemical formula is C16H20N2O4.

What grade and purity does Tech Serve Solutions supply for Boc-Trp-OH?

Tech Serve Solutions supplies Boc-Trp-OH with a purity of ≥99.0% (TLC). This product is supplied for research and laboratory use; TSS does not represent it as USP, BP, EP, or pharmacopoeia grade.

How should Boc-Trp-OH be handled safely?

When handling Boc-Trp-OH, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. The compound has a water hazard class of 3 (WGK 3) in Germany, indicating it requires careful handling to prevent environmental release.

How is Boc-Trp-OH packed and shipped?

Boc-Trp-OH is carefully packed and exported by Tech Serve Solutions to meet international shipping standards for fine chemicals, ensuring product integrity and safety during transit.

How can I request a quote or sample for Boc-Trp-OH?

To request a quote or a sample of Boc-Trp-OH, please contact our sales team through the Tech Serve Solutions website or your designated representative.