Boc-Trp-OSu
Nα-Boc-L-tryptophan hydroxysuccinimide ester (CAS: 3392-11-8), with the empirical formula C20H23N3O6 and molecular weight 401.41, is a protected tryptophan derivative. It serves as a valuable reagent in peptide synthesis and chemical biology research. This compound facilitates the introduction of tryptophan residues into peptide chains, crucial for studying protein structure and function. Its specific activation as a hydroxysuccinimide ester enhances coupling efficiency in solid-phase and solution-phase peptide synthesis.
- IUPAC
- Nα-Boc-L-tryptophan hydroxysuccinimide ester
- Synonyms
- Nα-Boc-L-tryptophan hydroxysuccinimide ester
Peptide Synthesis
Serves as an activated amino acid derivative for incorporating tryptophan into peptide sequences. The Nα-Boc protection and hydroxysuccinimide ester activation facilitate controlled peptide bond formation.
Chemical Biology
Utilised in the design and synthesis of peptides for probing biological pathways and protein interactions. Its structure allows for specific modifications and conjugation.
Chemical Synthesis
A versatile building block in organic synthesis, particularly for creating complex molecules containing the tryptophan moiety.
| Molecular weight | 401.41 |
|---|---|
| Empirical formula | C20H23N3O6 |
| Optical activity | [α]20/D −23.5±1.0°, c = 1% in dioxane |
| Storage temperature | −20°C |
| Melting point | 146-148 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Boc-L-tryptophan hydroxysuccinimide ester used for?
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Nα-Boc-L-tryptophan hydroxysuccinimide ester is primarily used in peptide synthesis to introduce tryptophan residues into peptide chains. It is also employed in chemical biology and general chemical synthesis.
What are the CAS number and formula for Nα-Boc-L-tryptophan hydroxysuccinimide ester?
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The CAS number is 3392-11-8 and the empirical formula is C20H23N3O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research-grade material. We do not represent it as USP, BP, EP, or any other pharmacopoeia standard.
How should Nα-Boc-L-tryptophan hydroxysuccinimide ester be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter (type N95 or P1) may be necessary. Avoid dust formation and ensure adequate ventilation. The compound has a GHS classification of WGK 3 in Germany.
How is Boc-Trp-OSu shipped and exported?
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This product is typically stored at −20°C. TSS exports fine chemicals globally, adhering to all relevant shipping and customs regulations.
How can I request a sample or quote for Boc-Trp-OSu?
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Please contact our sales team directly via our website or email to request a sample or a formal quotation.
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