Boc-Trp-N-carboxyanhydride
Nα-Boc-L-tryptophan Nα-carboxy anhydride (CAS: 175837-77-1), with empirical formula C17H18N2O5 and molecular weight 330.34, is a protected tryptophan derivative. This compound serves as a valuable intermediate in peptide synthesis and chemical biology research, enabling the controlled incorporation of tryptophan into peptide chains. It is supplied by TSS with an assay of ≥98.0% (CHN).
- IUPAC
- Nα-Boc-L-tryptophan Nα-carboxy anhydride
Peptide Synthesis
Nα-Boc-L-tryptophan Nα-carboxy anhydride is primarily used as a building block in solid-phase or solution-phase peptide synthesis. Its protected form allows for selective coupling reactions, facilitating the construction of complex peptide sequences containing tryptophan.
Chemical Biology Research
This compound is employed in chemical biology to synthesize modified peptides and peptidomimetics. It aids in the study of protein structure-function relationships, enzyme mechanisms, and the development of novel therapeutic agents.
Organic Synthesis Intermediate
As a reactive intermediate, it can be utilised in various organic transformations. Its structure lends itself to the synthesis of more complex molecules incorporating the indole side chain of tryptophan.
| Molecular weight | 330.34 |
|---|---|
| Empirical formula | C17H18N2O5 |
| Assay | ≥98.0% (CHN) |
| Optical activity | [α]20/D +78±5°, c = 1% in THF |
| Storage temperature | 2-8°C |
| Melting point | ~135 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Boc-L-tryptophan Nα-carboxy anhydride used for?
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Nα-Boc-L-tryptophan Nα-carboxy anhydride is primarily used as a protected building block in peptide synthesis and for applications in chemical biology research.
What is the CAS number and molecular formula for Nα-Boc-L-tryptophan Nα-carboxy anhydride?
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The CAS number is 175837-77-1 and the empirical formula is C17H18N2O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nα-Boc-L-tryptophan Nα-carboxy anhydride with an assay of ≥98.0% (CHN). This product is not represented as USP, BP, EP or other pharmacopoeia grade.
How should Nα-Boc-L-tryptophan Nα-carboxy anhydride be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Store at 2-8°C. The compound is also noted to decompose around 135°C.
Is Nα-Boc-L-tryptophan Nα-carboxy anhydride a controlled substance?
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The provided data does not indicate that Nα-Boc-L-tryptophan Nα-carboxy anhydride is a controlled substance.
How are your products shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, handling exportations according to international regulations.
How can I request a quote or sample?
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Please contact our sales team directly through the TSS website to request a quote or to inquire about obtaining a sample.
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