Boc-Thr-OH

CAS 2592-18-9CH3CH(OH)CH(COOH)NHCOOC(CH3)3Chemical Synthesis

Boc-Thr-OH (CAS 2592-18-9) is N-(tert-Butoxycarbonyl)-L-threonine, a protected amino acid derivative with the linear formula CH₃CH(OH)CH(COOH)NHCOOC(CH₃)₃ and a molecular weight of 219.23 g/mol. This compound is valuable in peptide synthesis and chemical biology for its role in building complex peptide chains. It is supplied by Tech Serve Solutions with an assay of ≥98.5% (T), requiring storage at -20°C.

IUPAC: N-(tert-Butoxycarbonyl)-L-threonine,Boc-L-threonine
Synonyms: N-(tert-Butoxycarbonyl)-L-threonineBoc-L-threonine

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Boc-Thr-OH (CH3CH(OH)CH(COOH)NHCOOC(CH3)3) — chemical structure, CAS 2592-18-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisPeptide ChemistryThreonine

01 /Applications

Peptide Synthesis

Boc-Thr-OH is a crucial building block in solid-phase and solution-phase peptide synthesis. The tert-butoxycarbonyl (Boc) protecting group on the amine facilitates controlled chain elongation, while the free carboxyl group allows for peptide bond formation.

Chemical Synthesis

As a derivative of L-threonine, this compound serves as a versatile intermediate in organic synthesis. Its protected functional groups enable selective modifications and the construction of more complex chiral molecules.

Chemical Biology Research

Boc-Thr-OH finds application in research aimed at understanding biological processes at a molecular level. It can be incorporated into peptides or peptidomimetics to study protein-protein interactions or enzyme mechanisms.

02 /Properties

Molecular weight	219.23
Linear formula	CH3CH(OH)CH(COOH)NHCOOC(CH3)3
Assay	≥98.5% (T)
Optical activity	[α]20/D −8.5±1°, c = 1% in acetic acid
Storage temperature	−20°C
Melting point	80-82 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

2592-18-9

MDL number

MFCD00065946

Beilstein registry

2051735

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-Thr-OH used for?

Boc-Thr-OH is primarily used as a protected amino acid in peptide synthesis, chemical synthesis, and chemical biology research. It serves as a building block for creating peptides and complex organic molecules.

What is the CAS number and formula for Boc-Thr-OH?

The CAS number for Boc-Thr-OH is 2592-18-9. Its linear formula is CH₃CH(OH)CH(COOH)NHCOOC(CH₃)₃.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Boc-Thr-OH with an assay of ≥98.5% (T). TSS does not represent this product as USP, BP, EP or other pharmacopoeia grades.

What are the safety and handling requirements for Boc-Thr-OH?

This compound requires careful handling. Recommended personal protective equipment includes eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is advised. It has a WGK rating of 3 in Germany.