Boc-Sta(3S,4S)-OH
Boc-Sta(3S,4S)-OH (CAS 58521-49-6) is a chiral, unnatural amino acid derivative with the molecular formula C13H25NO5 and a molecular weight of 275.34 g/mol. This compound is primarily utilised in peptide chemistry and as a building block for enzyme inhibitors. It serves as a non-hydrolyzable isostere for dipeptide units, finding applications in the rational design of protease inhibitors and substrate analogs. Boc-Sta(3S,4S)-OH is supplied by TSS for research and chemical synthesis purposes.
- IUPAC
- (3S,4S)-4-(Boc-amino)-3-hydroxy-6-methylheptanoic acid,Boc-statine
- Synonyms
- (3S,4S)-4-(Boc-amino)-3-hydroxy-6-methylheptanoic acidBoc-statine
Peptide Synthesis
Boc-Sta(3S,4S)-OH is a valuable unnatural amino acid for incorporating unique structural features into peptides. Its unnatural structure can enhance stability and modify biological activity.
Enzyme Inhibitor Design
This compound acts as a non-hydrolyzable isosteric replacement for dipeptide units in the design of synthetic peptide protease inhibitors. It is crucial for developing stable and effective therapeutic agents.
Chemical Biology Research
Boc-Sta(3S,4S)-OH serves as a key reagent in chemical biology for the synthesis of modified peptides and peptidomimetics, enabling the study of biological processes and enzyme mechanisms.
Substrate Analog Development
It is employed in the creation of substrate analogs that mimic natural enzyme substrates, aiding in the investigation of enzyme kinetics and the development of targeted enzyme modulators.
| Molecular weight | 275.34 |
|---|---|
| Empirical formula | C13H25NO5 |
| Assay | ~95% (sum of enantiomers, HPLC) |
| Optical activity | [α]20/D −41±2°, c = 0.5% in methanol |
| Storage temperature | 2-8°C |
| Application | (3S,4S)-Statine is often used as a non-hydrolyzable isosteric replacement for a dipeptide unit in design of synthetic peptide protease inhibitors.1 |
| Melting point | 119-122 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Sta(3S,4S)-OH used for?
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Boc-Sta(3S,4S)-OH is used in peptide synthesis, for the design of enzyme inhibitors, in chemical biology research, and for developing substrate analogs.
What is the CAS number and molecular formula for Boc-Sta(3S,4S)-OH?
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The CAS number is 58521-49-6, and the empirical formula is C13H25NO5.
What grade and purity does Tech Serve Solutions supply for Boc-Sta(3S,4S)-OH?
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Tech Serve Solutions supplies Boc-Sta(3S,4S)-OH with an assay of ~95% (sum of enantiomers, HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should Boc-Sta(3S,4S)-OH be handled and stored?
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Handle Boc-Sta(3S,4S)-OH with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator filter (type N95 or P1). Store at 2-8°C.
Is Boc-Sta(3S,4S)-OH a controlled substance?
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The provided data does not indicate that Boc-Sta(3S,4S)-OH is a controlled substance.
How is Boc-Sta(3S,4S)-OH packed and shipped by TSS?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging and shipping details for Boc-Sta(3S,4S)-OH are available upon request, adhering to all relevant regulations.
How can I request a quote or sample for Boc-Sta(3S,4S)-OH?
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To request a quote or sample for Boc-Sta(3S,4S)-OH, please contact the TSS sales department through our website or by phone.
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