Boc-Thr(PO3Me2)-OH
Nα-Boc-O-(dimethylphospho)-L-threonine (CAS: 162554-18-9) is a protected amino acid derivative with the molecular formula C11H22NO8P and a molecular weight of 327.27 g/mol. This compound serves as a valuable building block in complex organic synthesis, particularly within peptide chemistry and chemical biology research. Its structure incorporates a Boc-protected amine, a phosphodiester modification on the threonine side chain, and a free carboxylic acid, enabling diverse synthetic strategies.
- IUPAC
- Nα-Boc-O-(dimethylphospho)-L-threonine
- Synonyms
- Nα-Boc-O-(dimethylphospho)-L-threonine
Peptide Synthesis
Used as a modified amino acid in solid-phase or solution-phase peptide synthesis to introduce phosphodiester functionalities into peptide chains. This is crucial for creating phosphopeptides for biological studies.
Chemical Biology Research
Serves as a tool for investigating biological processes involving phosphorylated amino acids or peptides. It aids in the development of probes and inhibitors for studying kinase and phosphatase activities.
Organic Synthesis
Functions as a versatile intermediate in the synthesis of complex organic molecules, allowing for controlled introduction of modified threonine residues. Its protecting groups facilitate selective reactions.
| Molecular weight | 327.27 |
|---|---|
| Empirical formula | C11H22NO8P |
| Assay | ≥97.0% (TLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Boc-O-(dimethylphospho)-L-threonine used for?
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Nα-Boc-O-(dimethylphospho)-L-threonine is primarily used as a protected amino acid building block in peptide synthesis and for research in chemical biology and organic synthesis, particularly for introducing phosphodiester modifications.
What is the CAS number and molecular formula?
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The CAS number for Nα-Boc-O-(dimethylphospho)-L-threonine is 162554-18-9, and its empirical formula is C11H22NO8P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nα-Boc-O-(dimethylphospho)-L-threonine with a purity of ≥97.0% (determined by TLC). This product is supplied for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations?
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When handling Nα-Boc-O-(dimethylphospho)-L-threonine, it is recommended to use safety equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is advised. The compound has a WGK Germany rating of 3, indicating a high hazard level.
How is this chemical supplied and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. Nα-Boc-O-(dimethylphospho)-L-threonine is stored at 2-8°C to maintain its stability. Export documentation and packaging comply with international shipping regulations for chemical substances.
How can I request a sample or quote?
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To request a sample or a quotation for Nα-Boc-O-(dimethylphospho)-L-threonine, please contact our sales team through the website or via email, providing your contact details and the quantity required.
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