Boc-Ser-OH
Boc-Ser-OH (CAS: 3262-72-4) is an N-protected amino acid derivative, specifically N-(tert-Butoxycarbonyl)-L-serine. With a molecular weight of 205.21 g/mol, it serves as a crucial building block in peptide synthesis. Its structure allows for controlled elaboration of peptide chains. Boc-Ser-OH is also a valuable starting material for synthesising various alpha-amino acids through its beta-lactone intermediate, making it a versatile reagent in organic and medicinal chemistry research.
- IUPAC
- N-(tert-Butoxycarbonyl)-L-serine,Boc-L-serine
- Synonyms
- N-(tert-Butoxycarbonyl)-L-serineBoc-L-serine
Peptide Synthesis
Boc-Ser-OH is widely employed as a protected amino acid building block in solid-phase and solution-phase peptide synthesis. The tert-butoxycarbonyl (Boc) group protects the amine functionality during coupling reactions.
Synthesis of Amino Acid Derivatives
This compound acts as a starting material for the synthesis of diverse alpha-amino acids. It can be converted to a beta-lactone, which is then reacted further to yield various functionalised amino acid structures.
Chemical Biology Research
As a derivative of serine, Boc-Ser-OH finds application in chemical biology for creating modified peptides or probing biological pathways. Its specific protecting group and functional handles allow for targeted chemical modifications.
Organic Synthesis
Beyond peptide chemistry, Boc-Ser-OH is a useful intermediate in broader organic synthesis, enabling the introduction of a protected serine moiety into complex molecules.
| Molecular weight | 205.21 |
|---|---|
| Linear formula | HOCH2CH(COOH)NHCOOC(CH3)3 |
| Assay | ≥99.0% (T) |
| Optical activity | [α]20/D −3.5±0.5°, c = 2% in acetic acid |
| Storage temperature | 2-8°C |
| Application | Building block in peptide synthesis. Starting material for the synthesis of various α-amino acids via the β-lactone. |
| Melting point | 91 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Ser-OH primarily used for?
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Boc-Ser-OH (CAS: 3262-72-4) is primarily used as a building block in peptide synthesis and as a starting material for the synthesis of various alpha-amino acids via its beta-lactone intermediate.
What are the CAS number and molecular formula for Boc-Ser-OH?
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The CAS number for Boc-Ser-OH is 3262-72-4. Its linear formula is HOCH2CH(COOH)NHCOOC(CH3)3, and its molecular weight is 205.21 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Ser-OH with an assay of ≥99.0% (T). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Boc-Ser-OH be handled and stored safely?
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Handling Boc-Ser-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Store the compound at 2-8°C.
Is Boc-Ser-OH a controlled substance?
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The provided data does not indicate that Boc-Ser-OH is a controlled substance.
How is Boc-Ser-OH typically packed and shipped?
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Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging and shipping for chemicals like Boc-Ser-OH, adhering to international regulations for safe transport.
How can I request a sample or quote for Boc-Ser-OH?
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To request a sample or a quote for Boc-Ser-OH, please contact the Tech Serve Solutions sales department through our website or directly via email/phone, providing your specific requirements.
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