Boc-Ser(tBu)-OH (dicyclohexylammonium) salt
Boc-Ser(tBu)-OH (dicyclohexylammonium) salt (CAS 18942-50-2) is a protected amino acid derivative with the linear formula (CH3)3COCH2CH(COOH)NHCOOC(CH3)3 · C12H23N. This compound, with a molecular weight of 442.63, serves as a crucial building block in peptide synthesis and chemical biology research. Its protected nature allows for controlled incorporation into complex molecular structures, facilitating advancements in medicinal chemistry and biochemical studies.
- IUPAC
- Boc-O-tert-butyl-L-serine (dicyclohexylammonium) salt

Peptide Synthesis
Utilised as a protected serine derivative in solid-phase and solution-phase peptide synthesis. The Boc and tBu protecting groups ensure regioselective coupling and prevent side reactions during chain elongation.
Chemical Biology Research
Serves as a reagent for introducing modified serine residues into peptides or proteins to study biological functions and interactions. Its application aids in understanding enzyme mechanisms and protein structure-activity relationships.
Medicinal Chemistry
Employed in the development of novel therapeutic agents, particularly those involving peptide or peptidomimetic structures. It enables the synthesis of complex molecules with potential pharmaceutical applications.
Organic Synthesis
Acts as a chiral building block for the construction of complex organic molecules. Its defined stereochemistry and protected functional groups are valuable in multi-step synthetic routes.
| Molecular weight | 442.63 |
|---|---|
| Linear formula | (CH3)3COCH2CH(COOH)NHCOOC(CH3)3 · C12H23N |
| Assay | ≥99.0% (N) |
| Optical activity | [α]20/D +24.5±1.5°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 161-164 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Ser(tBu)-OH (dicyclohexylammonium) salt used for?
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Boc-Ser(tBu)-OH (dicyclohexylammonium) salt is primarily used as a protected building block in peptide synthesis and in chemical biology research for the controlled incorporation of modified serine residues.
What are the CAS number and formula for Boc-Ser(tBu)-OH (dicyclohexylammonium) salt?
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The CAS number is 18942-50-2. The linear formula is (CH3)3COCH2CH(COOH)NHCOOC(CH3)3 · C12H23N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Ser(tBu)-OH (dicyclohexylammonium) salt with an assay of ≥99.0% (N). This product is not represented as USP, BP, or EP grade.
How should Boc-Ser(tBu)-OH (dicyclohexylammonium) salt be handled and stored?
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Handle with appropriate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at 2-8°C.
Is Boc-Ser(tBu)-OH (dicyclohexylammonium) salt a controlled substance?
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Based on the provided data, there is no indication that this compound is a controlled substance.
How can I request a sample or quote for Boc-Ser(tBu)-OH (dicyclohexylammonium) salt?
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Please contact the Tech Serve Solutions sales team via the website or direct contact details to request a sample or a formal quotation.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Boc-Ser(tBu)-OH (dicyclohexylammonium) salt.
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