Boc-Ser(Bzl)-OH
N-(tert-Butoxycarbonyl)-O-benzyl-L-serine (CAS: 23680-31-1) is a protected amino acid derivative with a molecular weight of 295.33 g/mol. It features the tert-butoxycarbonyl (Boc) protecting group on the alpha-amino group and a benzyl protecting group on the serine side chain hydroxyl. This compound is a valuable building block in peptide synthesis and organic chemistry, primarily employed in research and development settings for constructing complex peptide chains and modified amino acid structures.
- IUPAC
- N-(tert-Butoxycarbonyl)-O-benzyl-L-serine,Boc-O-benzyl-L-serine
- Synonyms
- N-(tert-Butoxycarbonyl)-O-benzyl-L-serineBoc-Ser(Bzl)-OHBoc-O-benzyl-L-serine
Peptide Synthesis
As a protected amino acid, Boc-Ser(Bzl)-OH is crucial for solid-phase and solution-phase peptide synthesis. It allows for controlled, stepwise addition of serine residues into growing peptide chains while preventing unwanted side reactions.
Organic Synthesis
This compound serves as a chiral building block in the synthesis of various organic molecules. The presence of orthogonal protecting groups (Boc and Benzyl) enables selective deprotection strategies in multi-step synthetic routes.
Chemical Biology Research
It is utilized in the creation of modified peptides and peptidomimetics for biochemical and pharmacological studies. These modified peptides can be used to probe protein-protein interactions or develop new therapeutic agents.
| Molecular weight | 295.33 |
|---|---|
| Linear formula | C6H5CH2OCH2CH(COOH)NHCOOC(CH3)3 |
| Assay | ≥99.0% (T) |
| Optical activity | [α]20/D +20±1°, c = 2% in ethanol: water (4:1) |
| Melting point | 58-60 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(tert-Butoxycarbonyl)-O-benzyl-L-serine used for?
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N-(tert-Butoxycarbonyl)-O-benzyl-L-serine is primarily used as a protected amino acid building block in peptide synthesis and as a chiral intermediate in organic synthesis for constructing complex molecules and modified peptides.
What is the CAS number and chemical formula for this product?
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The CAS number is 23680-31-1. The linear formula is C<sub>6</sub>H<sub>5</sub>CH<sub>2</sub>OCH<sub>2</sub>CH(COOH)NHCOOC(CH<sub>3</sub>)<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-(tert-Butoxycarbonyl)-O-benzyl-L-serine with an assay of ≥99.0% (T). This product is supplied for research and laboratory use; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should Boc-Ser(Bzl)-OH be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a P1 (EN143) or N95 (US) respirator if airborne exposure is likely. It is classified under WGK Germany 3.
Is this chemical a controlled substance?
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The provided data does not indicate that N-(tert-Butoxycarbonyl)-O-benzyl-L-serine (CAS: 23680-31-1) is a controlled substance.
How is this chemical packed and shipped?
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Products are carefully packed and exported by Tech Serve Solutions, adhering to international shipping regulations for chemicals. Specific packaging details are available upon request.
How can I request a quote or sample?
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To request a quote or a sample of N-(tert-Butoxycarbonyl)-O-benzyl-L-serine, please contact our sales department through the website or by phone, referencing the product name and CAS number.
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