Boc-Tyr(3,5-I2)-OSu
Boc-Tyr(3,5-I2)-OSu (CAS: 163679-35-4) is a Boc-protected, iodinated tyrosine derivative featuring a hydroxysuccinimide ester. With a molecular weight of 630.17 g/mol, this compound is a valuable building block in chemical biology and peptide synthesis. Its specific structure allows for targeted modifications and incorporation into peptides, facilitating the study of protein function and the development of novel therapeutic agents.
- IUPAC
- Boc-3,5-diiodo-L-tyrosine hydroxysuccinimide ester
- Synonyms
- Boc-3,5-diiodo-L-tyrosine hydroxysuccinimide ester
Peptide Synthesis
Used as a key intermediate in solid-phase or solution-phase peptide synthesis. Its activated ester facilitates coupling to amino groups, enabling the introduction of modified tyrosine residues into peptide chains.
Chemical Biology Research
Serves as a valuable reagent for labeling and modifying biomolecules. The iodine atoms and activated ester can be utilized in various biochemical assays and studies of protein-ligand interactions.
Drug Discovery
Incorporated into peptide-based drug candidates to enhance stability, bioavailability, or targeting. The unnatural amino acid derivative can confer unique pharmacological properties.
Bioconjugation
The reactive hydroxysuccinimide ester allows for covalent conjugation to amine-containing molecules, such as proteins or antibodies, for applications in diagnostics or targeted delivery systems.
| Molecular weight | 630.17 |
|---|---|
| Empirical formula | C18H20I2N2O7 |
| Assay | ≥97.0% (calc. based on dry substance, C/N) |
| Optical activity | [α]20/D +17±1°, c = 1% in chloroform |
| Storage temperature | −20°C |
| Melting point | 144-148 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Tyr(3,5-I2)-OSu used for?
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Boc-Tyr(3,5-I2)-OSu is primarily used in peptide synthesis, chemical biology research, drug discovery, and bioconjugation due to its structure as a Boc-protected, iodinated tyrosine derivative with an activated ester.
What is the CAS number and molecular formula for Boc-Tyr(3,5-I2)-OSu?
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The CAS number is 163679-35-4 and the molecular formula is C18H20I2N2O7.
What grade and purity does Tech Serve Solutions supply for Boc-Tyr(3,5-I2)-OSu?
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Tech Serve Solutions supplies Boc-Tyr(3,5-I2)-OSu with a purity of ≥97.0% (calc. based on dry substance, C/N). This is a research grade material and is not supplied as USP, BP, or EP grade.
How should Boc-Tyr(3,5-I2)-OSu be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound should be stored at −20°C.
Is Boc-Tyr(3,5-I2)-OSu a controlled substance?
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The provided data does not indicate that Boc-Tyr(3,5-I2)-OSu is a controlled substance.
How is Boc-Tyr(3,5-I2)-OSu packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging for safe transport in compliance with international regulations. Specific packaging details are available upon request.
How can I request a sample or a quote for Boc-Tyr(3,5-I2)-OSu?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number (163679-35-4).
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