1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene monooxide
1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene monooxide (CAS 638132-66-8) is a chiral phosphine oxide ligand with the molecular formula C18H28OP2 and a molecular weight of 322.36 g/mol. This compound is primarily utilised in asymmetric synthesis as a privileged ligand in catalysis, facilitating stereoselective chemical transformations. Its specific structure enables high enantioselectivity in various catalytic reactions, making it a valuable reagent for fine chemical and pharmaceutical intermediate synthesis.
- IUPAC
- (2R,5R)-1-{2-[(2R,5R)-2,5-Dimethylphospholan-1-yl]phenyl}-2,5-dimethylphospholane 1-oxide,R,R-Me-BozPhos
- Synonyms
- R,R-Me-BozPhos(2R,5R)-1-{2-[(2R,5R)-2,5-Dimethylphospholan-1-yl]phenyl}-2,5-dimethylphospholane 1-oxide
![1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene monooxide (5R)-2) — chemical structure, CAS 638132-66-8; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F638132-66-8.png&w=3840&q=75)
Asymmetric Catalysis
This compound functions as a chiral ligand in transition metal catalysis, promoting enantioselective synthesis of chiral molecules. It is particularly effective in reactions requiring high stereocontrol, such as asymmetric hydrogenation and C-C bond formation.
Ligand for Privileged Complexes
As a member of the DuPhos/BPE family, this phospholane oxide is recognised as a privileged ligand. It forms highly efficient catalytic complexes with transition metals, enabling advanced synthetic methodologies in organic chemistry.
Chemical Synthesis Reagent
It serves as a key component in complex chemical synthesis pathways, offering stereochemical control. Its application is vital for producing enantiomerically pure compounds used in pharmaceuticals and advanced materials.
| Molecular weight | 322.36 |
|---|---|
| Empirical formula | C18H28OP2 |
| Optical activity | [α]22/D -171°, c = 1 in chloroform |
| Application | DuPhos and BPE Ligands: Highly Efficient Privileged Ligands |
| Melting point | 116-122 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene monooxide used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis and catalysis, facilitating stereoselective chemical transformations and forming privileged catalytic complexes.
What is the CAS number and chemical formula for this product?
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The CAS number is 638132-66-8, and the empirical formula (in Hill notation) is C18H28OP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and synthesis purposes. The specific grade and purity will be detailed on the Certificate of Analysis provided with your order. We do not represent this product as USP, BP, or EP grade.
How should 1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene monooxide be handled and stored?
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Based on available safety data, this compound is classified under WGK Germany 3. Handle with appropriate personal protective equipment in a well-ventilated area. Store in a cool, dry place away from incompatible materials. Refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, including this compound.
How can I request a sample or quote for this chemical?
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To request a sample or obtain a quote, please use the contact form on our website or contact our sales department directly, referencing the product name and CAS number 638132-66-8.
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