1,2-Bis[(2R,5R)-2,5-diisopropylphospholano]ethane
1,2-Bis[(2R,5R)-2,5-diisopropylphospholano]ethane (CAS 136705-63-0), with the molecular formula C22H44P2 and a molecular weight of 370.53 g/mol, is a chiral diphosphine ligand. It is a key component in asymmetric synthesis, particularly recognised for its role in catalysis. This compound is invaluable in creating enantiomerically pure substances, finding significant application in the pharmaceutical and fine chemical industries.
- Synonyms
- 5R)-2,5-diisopropylphospholano]ethane
![1,2-Bis[(2R,5R)-2,5-diisopropylphospholano]ethane (5R)-2) — chemical structure, CAS 136705-63-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F136705-63-0.png&w=3840&q=75)
Asymmetric Catalysis
This ligand is extensively used in transition metal-catalysed asymmetric reactions, enabling the stereoselective formation of chiral molecules. Its structure facilitates high enantioselectivity in various transformations.
Pharmaceutical Synthesis
It plays a crucial role in the synthesis of active pharmaceutical ingredients (APIs) where specific stereochemistry is required for efficacy and safety. This enables the production of complex chiral drugs.
Fine Chemical Production
The ligand is employed in the manufacturing of high-value fine chemicals, promoting efficient and selective synthesis pathways. It aids in achieving desired product purity and specific enantiomeric excess.
Ligand for Metal Complexes
It serves as a privileged ligand, forming stable and catalytically active complexes with various transition metals. These complexes are instrumental in driving a range of organic transformations.
| Molecular weight | 370.53 |
|---|---|
| Empirical formula | C22H44P2 |
| Application | DuPhos and BPE Ligands: Highly Efficient Privileged Ligands |
| Melting point | 67-72 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Bis[(2R,5R)-2,5-diisopropylphospholano]ethane used for?
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This compound is primarily used as a chiral diphosphine ligand in asymmetric synthesis and catalysis, particularly in the pharmaceutical and fine chemical industries for producing enantiomerically pure substances.
What are the CAS number and formula for 1,2-Bis[(2R,5R)-2,5-diisopropylphospholano]ethane?
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The CAS number is 136705-63-0, and the empirical formula is C22H44P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a specified purity based on the product's specifications. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the product data.
How should 1,2-Bis[(2R,5R)-2,5-diisopropylphospholano]ethane be handled?
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According to the safety data, this compound is classified under WGK 2 in Germany. Appropriate personal protective equipment should be used, and it should be handled in a well-ventilated area, avoiding contact with skin, eyes, and clothing.
Can I request a sample or a quote for this product?
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Yes, please contact our sales team via the website or direct email to request a sample or obtain a quotation for 1,2-Bis[(2R,5R)-2,5-diisopropylphospholano]ethane.
How is this chemical shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, ensuring compliant packaging and documentation for international shipments of 1,2-Bis[(2R,5R)-2,5-diisopropylphospholano]ethane.
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