1,2-Bis[(2R,5R)-2,5-diphenylphospholano]ethane(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate
1,2-Bis[(2R,5R)-2,5-diphenylphospholano]ethane(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate (CAS: 528565-84-6) is a rhodium-based organometallic complex with a molecular weight of 804.49 g/mol. This chiral catalyst, featuring the privileged DuPhos ligand system, is extensively utilised in asymmetric synthesis for the enantioselective preparation of chiral compounds, particularly in the pharmaceutical and fine chemical industries.
- IUPAC
- (R,R)-Ph-BPE-Rh
- Synonyms
- 5R)-2, 5-diphenylphospholano]ethane(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate
![1,2-Bis[(2R,5R)-2,5-diphenylphospholano]ethane(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate (5R)-2) — chemical structure, CAS 528565-84-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F528565-84-6.png&w=3840&q=75)
Asymmetric Catalysis
This rhodium complex serves as a highly effective catalyst in asymmetric hydrogenation and other enantioselective transformations. Its chiral phospholane ligands enable the precise control of stereochemistry in the synthesis of valuable chiral molecules.
Pharmaceutical Intermediate Synthesis
It is instrumental in the production of enantiomerically pure intermediates for active pharmaceutical ingredients (APIs). The catalyst facilitates the stereoselective formation of chiral centres crucial for drug efficacy and safety.
Fine Chemical Manufacturing
The compound finds application in the synthesis of complex chiral fine chemicals where high enantiomeric purity is a critical requirement. Its efficiency and selectivity contribute to streamlined manufacturing processes.
Ligand and Catalyst Research
As a representative of the privileged DuPhos/BPE ligand class, this complex is a subject of research in developing new catalytic systems and understanding mechanisms in asymmetric catalysis.
| Molecular weight | 804.49 |
|---|---|
| Empirical formula | C42H48BF4P2Rh |
| Application | DuPhos and BPE Ligands: Highly Efficient Privileged Ligands |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Bis[(2R,5R)-2,5-diphenylphospholano]ethane(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate used for?
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This compound is primarily used as a chiral catalyst in asymmetric synthesis, particularly for enantioselective transformations like hydrogenation, aiding in the production of chiral pharmaceuticals and fine chemicals.
What are the CAS number and formula for this chemical?
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The CAS number is 528565-84-6, and its empirical formula (Hill notation) is C42H48BF4P2Rh.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research and chemical synthesis purposes. The specific grade and purity are detailed in the product specifications, and it is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should 1,2-Bis[(2R,5R)-2,5-diphenylphospholano]ethane(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate be handled?
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As indicated by GHS07 and a Warning signal word, this compound may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves, should be used. Ensure adequate ventilation.
Is this chemical a controlled substance?
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The provided data does not indicate that this chemical is a controlled substance.
How is this product shipped or exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, handling shipments and exports in compliance with international regulations.
How can I request a sample or quote?
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Please contact our sales team via the website or provided contact details to request a sample or a formal quotation for this product.
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