1,2-Bis[(2S,5S)-2,5-diisopropylphospholano]ethane
1,2-Bis[(2S,5S)-2,5-diisopropylphospholano]ethane (CAS 528854-34-4) is a chiral diphosphine ligand with the molecular formula C22H44P2 and a molecular weight of 370.53 g/mol. It is a key component in asymmetric synthesis, facilitating enantioselective transformations. This compound is recognised for its effectiveness in various catalytic applications, enabling the precise synthesis of chiral molecules vital in pharmaceutical and fine chemical industries.
- Synonyms
- 1,2-Bis[(2S,5S)-2,5-diisopropylphospholano]ethane5S)-2,5-diisopropylphospholano]ethane
![1,2-Bis[(2S,5S)-2,5-diisopropylphospholano]ethane (5S)-2) — chemical structure, CAS 528854-34-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F528854-34-4.png&w=3840&q=75)
Asymmetric Catalysis
This diphosphine ligand is widely employed as a chiral auxiliary in transition metal catalysis. It enables highly enantioselective reactions, crucial for the synthesis of stereochemically pure compounds.
Chiral Ligand
As a member of the DuPhos/BPE class of privileged ligands, it forms highly active and selective catalysts. Its structure allows for fine-tuning of catalytic performance in complex organic transformations.
Pharmaceutical Intermediate Synthesis
The ability to control stereochemistry makes this ligand invaluable in the synthesis of chiral pharmaceutical intermediates, contributing to the efficient production of active pharmaceutical ingredients.
Fine Chemical Production
It plays a significant role in the manufacture of complex fine chemicals where specific enantiomers are required, ensuring high purity and desired product characteristics.
| Molecular weight | 370.53 |
|---|---|
| Empirical formula | C22H44P2 |
| Application | DuPhos and BPE Ligands: Highly Efficient Privileged Ligands |
| Melting point | 67-72 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Bis[(2S,5S)-2,5-diisopropylphospholano]ethane used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis, particularly in metal-catalyzed reactions for the synthesis of enantiomerically enriched compounds, including pharmaceutical intermediates and fine chemicals.
What is the CAS number and formula for this chemical?
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The CAS number is 528854-34-4 and the molecular formula is C22H44P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical typically as a research or technical grade. Specific purity information can be obtained from the Certificate of Analysis. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated in the product specifications.
How should 1,2-Bis[(2S,5S)-2,5-diisopropylphospholano]ethane be handled?
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According to safety data, this compound may cause skin irritation and serious eye irritation. Appropriate personal protective equipment, including gloves and eye protection, should be worn. Handle in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling and safety information.
Is this chemical a controlled substance?
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Based on the provided data, this chemical is not classified as a controlled substance.
How is this product packed and exported?
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Tech Serve Solutions packs and exports chemicals with adherence to international shipping regulations to ensure safe and compliant delivery worldwide.
How can I request a sample or quote?
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To request a sample or a quote for 1,2-Bis[(2S,5S)-2,5-diisopropylphospholano]ethane, please contact our sales department through the website or by phone, providing the product name and CAS number.
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