1,2-Bis[(2S,5S)-2,5-dimethylphospholano]benzene(cyclooctadiene)rhodium(I) trifluoromethanesulfonate
1,2-Bis[(2S,5S)-2,5-dimethylphospholano]benzene(cyclooctadiene)rhodium(I) trifluoromethanesulfonate (CAS: 136705-75-4) is a chiral rhodium catalyst with the empirical formula C27H40F3O3P2RhS and a molecular weight of 666.52 g/mol. This compound is a key reagent in asymmetric synthesis, particularly valuable for facilitating enantioselective transformations. Its structure, featuring bulky phospholane ligands, enables high stereocontrol in various catalytic reactions, making it an important tool for producing chiral molecules.
- Synonyms
- 1,2-Bis[(2S,5S)-2,5-dimethylphospholano]benzene(cyclooctadiene)rhodium(I) trifluoromethanesulfonate5S)-2,5-dimethylphospholano]benzene(cyclooctadiene)rhodium(I) trifluoromethanesulfonate136705-75-4C27H40F3O3P2RhS
![1,2-Bis[(2S,5S)-2,5-dimethylphospholano]benzene(cyclooctadiene)rhodium(I) trifluoromethanesulfonate (5S)-2) — chemical structure, CAS 136705-75-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F136705-75-4.png&w=3840&q=75)
Asymmetric Catalysis
This rhodium complex acts as a powerful catalyst for asymmetric hydrogenation and other enantioselective reactions. It is particularly effective in creating chiral centres with high enantiomeric excess, crucial for the synthesis of enantiopure pharmaceuticals and fine chemicals.
Chiral Ligand Applications
The (2S,5S)-2,5-dimethylphospholano ligands coordinated to rhodium are instrumental in achieving stereoselectivity. These privileged ligands are well-established for their efficacy in facilitating challenging asymmetric transformations where precise stereochemical control is paramount.
Chemical Synthesis Reagent
As a sophisticated reagent, it is employed in advanced chemical synthesis pathways. Its application aids in the development of complex molecules by introducing chirality efficiently and predictably, supporting research and development in medicinal chemistry and materials science.
| Molecular weight | 666.52 |
|---|---|
| Empirical formula | C27H40F3O3P2RhS |
| Assay | 97% |
| Application | DuPhos and BPE Ligands: Highly Efficient Privileged Ligands |
| Melting point | 136.0-154.7 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Bis[(2S,5S)-2,5-dimethylphospholano]benzene(cyclooctadiene)rhodium(I) trifluoromethanesulfonate used for?
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This compound is primarily used as a chiral catalyst in asymmetric synthesis, facilitating enantioselective transformations such as hydrogenation, crucial for producing enantiopure compounds.
What are the CAS number and formula for this rhodium complex?
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The CAS number is 136705-75-4, and the empirical formula (Hill notation) is C27H40F3O3P2RhS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a purity of 97%. This is a research-grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should this chemical be handled safely?
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Handle with appropriate personal protective equipment: a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation as it may cause skin, eye, and respiratory irritation (H315-H319-H335).
How is this product packaged, shipped, and exported?
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Tech Serve Solutions can professionally package, ship, and export this chemical globally, adhering to all relevant transport and regulatory requirements.
How can I request a sample or quote for this product?
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To request a sample or quote, please contact our sales department via the website or by telephone, providing the product name and CAS number (136705-75-4).
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